纳米颗粒在兽药领域的应用。

IF 2.8 Q1 VETERINARY SCIENCES International Journal of Veterinary Science and Medicine Pub Date : 2019-12-26 eCollection Date: 2019-01-01 DOI:10.1080/23144599.2019.1691379
Fady Sayed Youssef, Hossny Awad El-Banna, Hesham Youssef Elzorba, Ahmed Mohamed Galal
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引用次数: 52

摘要

纳米技术是一项快速发展的技术,在各个领域的治疗应用中发挥着重要的作用。它能够解决与动物健康和生产有关的几个问题。有不同的纳米系统,如脂质体、金属纳米粒子、聚合物胶束、聚合物纳米球、功能化富勒烯、碳纳米管、树状大分子、聚合物包被纳米晶体和纳米壳。本文综述了纳米颗粒的制备方法和表征方法。本文主要综述了生物利用度差、副作用多的纳米颗粒给药系统。纳米粒子具有体积小、表面积大、质量大等特点。纳米颗粒抗菌剂系统的发展被认为是一种极好的抗菌剂替代递送系统,可以通过增加治疗效果和克服副作用来治疗微生物疾病。本文综述了几种抗菌纳米颗粒制剂,重点介绍了氟苯尼考和新霉素纳米颗粒制剂以及壳聚糖和银纳米颗粒制剂的制备、表征和不同药理作用的比较。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Application of some nanoparticles in the field of veterinary medicine.

Nanotechnology is a fast-growing technology that plays an important great impact on various fields of therapeutic applications. It is capable for solving several problems related to animal health and production. There are different nano-systems such as liposomes, metallic nanoparticles, polymeric micelles, polymeric nanospheres, functionalized fullerenes, carbon nanotubes, dendrimers, polymer-coated nanocrystals and nanoshells. In this review, we mentioned different methods for the preparation and characterization of nanoparticles. This review is concerned mainly on nanoparticle systems for antibiotic delivery which suffer from poor bioavailability and many side effects. Nanoparticles are characterized by many features include their minimal size, colossal surface zone to mass extent. The development of antimicrobials in nanoparticle systems is considered an excellent alternative delivery system for antimicrobials for the treatment of microbial diseases by increasing therapeutic effect and overcoming the side effects. In this paper, we reviewed some antimicrobial nanoparticle preparations and we focused on florfenicol and neomycin nanoparticle preparations as well as chitosan and silver nanoparticles preparations to prepare, characterize and compare their different pharmacological effects.

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来源期刊
CiteScore
4.80
自引率
0.00%
发文量
12
审稿时长
24 weeks
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