IL-8作为格林-巴利综合征的潜在生物标志物。

IF 2.2 4区医学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY European cytokine network Pub Date : 2019-12-01 DOI:10.1684/ecn.2019.0436

Gautier Breville, Agustina M Lascano, Pascale Roux-Lombard, Patrice H Lalive

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引用次数: 9

摘要

本初步研究旨在比较格林-巴利综合征(GBS)、慢性炎症性脱髓鞘多神经病变(CIDP)、非炎症性多神经病变(PNP)和其他非炎症性神经疾病(功能综合征或偏头痛)患者脑脊液(CSF)中促炎趋化因子白介素-8 (IL-8)的水平。结果显示，与其他组相比，GBS患者CSF IL-8水平升高(p

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IL-8 as a potential biomarker in Guillain-Barre Syndrome.

This pilot study was designed to compare the levels of interleukin-8 (IL-8), a pro-inflammatory chemokine, in the cerebrospinal fluid (CSF) of patients with Guillain-Barre syndrome (GBS), chronic inflammatory demyelinating polyneuropathy (CIDP), non-inflammatory polyneuropathy (PNP), and other non-inflammatory neurological diseases (functional syndrome or migraine). The results show elevated CSF IL-8 levels in GBS compared to the other groups (p < 0.05). IL-8 could be considered a potential biomarker to differentiate GBS from CIDP. This distinction could be relevant in terms of therapeutic decisions and functional prognosis.

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来源期刊

European cytokine network 生物-免疫学

CiteScore

5.70

自引率

0.00%

发文量

审稿时长

6 months

期刊介绍： The journal that brings together all areas of work involving cytokines. European Cytokine Network is an electronic journal that publishes original articles and abstracts every quarter to provide an essential bridge between researchers and clinicians with an interest in this cutting-edge field. The journal has become a must-read for specialists in the field thanks to its swift publication and international circulation. The journal is referenced in several databases, including Medline, which is testament to its scientific quality.