igg4相关肺部疾病侵犯横膈膜1例

IF 1.1 4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Annals of Thoracic and Cardiovascular Surgery Pub Date : 2022-06-20 Epub Date: 2020-02-27 DOI:10.5761/atcs.cr.19-00244
Yuki Ono, Gouji Toyokawa, Tetsuzo Tagawa, Kayo Ijichi, Yoshinao Oda, Masaki Mori
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引用次数: 3

摘要

免疫球蛋白g4相关疾病(IgG4-RD)是一种累及多器官的纤维炎性疾病。这是一个非常罕见的igg4相关肺部疾病(IgG4-RLD)侵犯膈肌的病例。患者为71岁男性,长期接触石棉,左下肺叶肿块影,CT检查怀疑侵犯左膈。正电子发射断层扫描(PET)/CT也显示肿块大量摄入氟脱氧葡萄糖,怀疑为肺癌。虽然支气管镜活检不能明确诊断,但我们行左下肺叶切除联合左膈切除术。标本病理表现为IgG4- rld特征:静脉狭窄,静脉周围纤维化,IgG4阳性细胞浸润,IgG细胞与IgG4细胞的比例为40%。此外,有炎症细胞浸润到膈肌。
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IgG4-Related Lung Disease Exhibiting the Invasion into the Diaphragm: A Case Report.

Immunoglobulin G4-related disease (IgG4-RD) is a fibroinflammatory condition which involves various organs. This is a very rare case of IgG4-related lung disease (IgG4-RLD) with the invasion into diaphragm. The patient was a 71-year-old man with a long-term exposure to asbestos who had a mass shadow in the left lower lung lobe, which was suspected to invade the left diaphragm on computed tomography (CT). Positron emission tomography (PET)/CT also presented an avid intake of fluorodeoxyglucose in the mass, which suspected lung cancer. Although bronchoscopic biopsy could not lead to the definite diagnosis, we performed left lower lobectomy combined with the resection of left diaphragm. The specimen showed the features of IgG4-RLD on pathology: the vein stenosis and fibrosis around the vein, the infiltration of IgG4-positive cells, and IgG cells to IgG4 cells ratio of 40%. Furthermore, there were inflammatory cells infiltrating to the diaphragm.

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来源期刊
Annals of Thoracic and Cardiovascular Surgery
Annals of Thoracic and Cardiovascular Surgery CARDIAC & CARDIOVASCULAR SYSTEMS-SURGERY
CiteScore
2.80
自引率
0.00%
发文量
56
审稿时长
4-8 weeks
期刊介绍: Information not localized
期刊最新文献
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