N Rolle, M Muruganandam, I Jan, F M Harji, J Harrington, K N Konstantinov
{"title":"肉芽肿合并多血管炎(GPA)直接面对:错过机会导致延误诊断。","authors":"N Rolle, M Muruganandam, I Jan, F M Harji, J Harrington, K N Konstantinov","doi":"10.1186/s13317-019-0118-4","DOIUrl":null,"url":null,"abstract":"<p><p>Granulomatosis with polyangiitis (GPA) is a systemic vasculitis with a potential to involve any organ system. It remains an important cause of kidney related morbidity and mortality. Early diagnosis can be difficult and requires high index of suspicion in all patients, but especially in cases with atypical presentation. We report a case with GPA, which was diagnosed only after new and advancing symptoms belied the original diagnosis of bilateral facial palsy and aortic mural thrombus.</p>","PeriodicalId":8655,"journal":{"name":"Auto-Immunity Highlights","volume":"10 1","pages":"8"},"PeriodicalIF":0.0000,"publicationDate":"2019-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13317-019-0118-4","citationCount":"0","resultStr":"{\"title\":\"Look granulomatosis with polyangiitis (GPA) straight in the face: missed opportunities leading to a delayed diagnosis.\",\"authors\":\"N Rolle, M Muruganandam, I Jan, F M Harji, J Harrington, K N Konstantinov\",\"doi\":\"10.1186/s13317-019-0118-4\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Granulomatosis with polyangiitis (GPA) is a systemic vasculitis with a potential to involve any organ system. It remains an important cause of kidney related morbidity and mortality. Early diagnosis can be difficult and requires high index of suspicion in all patients, but especially in cases with atypical presentation. We report a case with GPA, which was diagnosed only after new and advancing symptoms belied the original diagnosis of bilateral facial palsy and aortic mural thrombus.</p>\",\"PeriodicalId\":8655,\"journal\":{\"name\":\"Auto-Immunity Highlights\",\"volume\":\"10 1\",\"pages\":\"8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-09-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1186/s13317-019-0118-4\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Auto-Immunity Highlights\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1186/s13317-019-0118-4\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2019/12/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q1\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Auto-Immunity Highlights","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1186/s13317-019-0118-4","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2019/12/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"Medicine","Score":null,"Total":0}
Look granulomatosis with polyangiitis (GPA) straight in the face: missed opportunities leading to a delayed diagnosis.
Granulomatosis with polyangiitis (GPA) is a systemic vasculitis with a potential to involve any organ system. It remains an important cause of kidney related morbidity and mortality. Early diagnosis can be difficult and requires high index of suspicion in all patients, but especially in cases with atypical presentation. We report a case with GPA, which was diagnosed only after new and advancing symptoms belied the original diagnosis of bilateral facial palsy and aortic mural thrombus.