自体骨关节体外辐照移植治疗恶性骨肿瘤的临床疗效。

Q2 Medicine Sarcoma Pub Date : 2020-03-30 eCollection Date: 2020-01-01 DOI:10.1155/2020/9672093
Satoshi Takenaka, Nobuhito Araki, Takafumi Ueda, Shigeki Kakunaga, Yoshinori Imura, Ken-Ichiro Hamada, Hidetatsu Outani, Norifumi Naka, Akira Myoui, Hideki Yoshikawa
{"title":"自体骨关节体外辐照移植治疗恶性骨肿瘤的临床疗效。","authors":"Satoshi Takenaka,&nbsp;Nobuhito Araki,&nbsp;Takafumi Ueda,&nbsp;Shigeki Kakunaga,&nbsp;Yoshinori Imura,&nbsp;Ken-Ichiro Hamada,&nbsp;Hidetatsu Outani,&nbsp;Norifumi Naka,&nbsp;Akira Myoui,&nbsp;Hideki Yoshikawa","doi":"10.1155/2020/9672093","DOIUrl":null,"url":null,"abstract":"<p><strong>Methods: </strong>We retrospectively reviewed 33 patients who underwent osteoarticular ECIA after bone tumor resection from 1988 to 2014. We investigated complications, radiographic changes by the International Society of Limb Salvage graft evaluation criteria, and functional outcomes according to the Musculoskeletal Tumor Society scoring system.</p><p><strong>Results: </strong>Fifteen patients were reoperated upon due to infection (<i>n</i> = 9), protruding fixation implant (<i>n</i> = 4), or fracture of the grafted bone (<i>n</i> = 2). The average radiographic evaluation score was 66.4%, and the median functional score was 23 (77%). The radiographic score for the proximal humerus or proximal tibia was lower than that for the other locations. The functional score was not different among the autograft sites but was related to the radiographic score.</p><p><strong>Conclusion: </strong>Although osteoarticular ECIA is one of the reasonable surgical options for patients with tumors for which reliable prostheses are not available, we do not recommend osteoarticular ECIA as a routine procedure because of high complication rate.</p>","PeriodicalId":21431,"journal":{"name":"Sarcoma","volume":"2020 ","pages":"9672093"},"PeriodicalIF":0.0000,"publicationDate":"2020-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2020/9672093","citationCount":"8","resultStr":"{\"title\":\"Clinical Outcomes of Osteoarticular Extracorporeal Irradiated Autograft for Malignant Bone Tumor.\",\"authors\":\"Satoshi Takenaka,&nbsp;Nobuhito Araki,&nbsp;Takafumi Ueda,&nbsp;Shigeki Kakunaga,&nbsp;Yoshinori Imura,&nbsp;Ken-Ichiro Hamada,&nbsp;Hidetatsu Outani,&nbsp;Norifumi Naka,&nbsp;Akira Myoui,&nbsp;Hideki Yoshikawa\",\"doi\":\"10.1155/2020/9672093\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Methods: </strong>We retrospectively reviewed 33 patients who underwent osteoarticular ECIA after bone tumor resection from 1988 to 2014. We investigated complications, radiographic changes by the International Society of Limb Salvage graft evaluation criteria, and functional outcomes according to the Musculoskeletal Tumor Society scoring system.</p><p><strong>Results: </strong>Fifteen patients were reoperated upon due to infection (<i>n</i> = 9), protruding fixation implant (<i>n</i> = 4), or fracture of the grafted bone (<i>n</i> = 2). The average radiographic evaluation score was 66.4%, and the median functional score was 23 (77%). The radiographic score for the proximal humerus or proximal tibia was lower than that for the other locations. The functional score was not different among the autograft sites but was related to the radiographic score.</p><p><strong>Conclusion: </strong>Although osteoarticular ECIA is one of the reasonable surgical options for patients with tumors for which reliable prostheses are not available, we do not recommend osteoarticular ECIA as a routine procedure because of high complication rate.</p>\",\"PeriodicalId\":21431,\"journal\":{\"name\":\"Sarcoma\",\"volume\":\"2020 \",\"pages\":\"9672093\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-03-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1155/2020/9672093\",\"citationCount\":\"8\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Sarcoma\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1155/2020/9672093\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2020/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sarcoma","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/2020/9672093","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2020/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 8

摘要

方法:回顾性分析1988 ~ 2014年33例骨肿瘤切除术后行骨关节ECIA的患者。我们根据国际残肢移植评估标准调查了并发症、影像学变化,并根据肌肉骨骼肿瘤协会评分系统调查了功能结果。结果:15例患者因感染(n = 9)、内固定物突出(n = 4)或移植物骨折(n = 2)再次手术。平均影像学评分为66.4%,中位功能评分为23分(77%)。肱骨近端或胫骨近端x线评分低于其他部位。功能评分在自体移植物部位间无差异,但与影像学评分相关。结论:虽然骨关节ECIA是无法获得可靠假体的肿瘤患者的合理手术选择之一,但由于并发症发生率高,我们不建议将骨关节ECIA作为常规手术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

摘要图片

摘要图片

摘要图片

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Clinical Outcomes of Osteoarticular Extracorporeal Irradiated Autograft for Malignant Bone Tumor.

Methods: We retrospectively reviewed 33 patients who underwent osteoarticular ECIA after bone tumor resection from 1988 to 2014. We investigated complications, radiographic changes by the International Society of Limb Salvage graft evaluation criteria, and functional outcomes according to the Musculoskeletal Tumor Society scoring system.

Results: Fifteen patients were reoperated upon due to infection (n = 9), protruding fixation implant (n = 4), or fracture of the grafted bone (n = 2). The average radiographic evaluation score was 66.4%, and the median functional score was 23 (77%). The radiographic score for the proximal humerus or proximal tibia was lower than that for the other locations. The functional score was not different among the autograft sites but was related to the radiographic score.

Conclusion: Although osteoarticular ECIA is one of the reasonable surgical options for patients with tumors for which reliable prostheses are not available, we do not recommend osteoarticular ECIA as a routine procedure because of high complication rate.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Sarcoma
Sarcoma Medicine-Radiology, Nuclear Medicine and Imaging
CiteScore
5.00
自引率
0.00%
发文量
15
审稿时长
14 weeks
期刊介绍: Sarcoma is dedicated to publishing papers covering all aspects of connective tissue oncology research. It brings together work from scientists and clinicians carrying out a broad range of research in this field, including the basic sciences, molecular biology and pathology and the clinical sciences of epidemiology, surgery, radiotherapy and chemotherapy. High-quality papers concerning the entire range of bone and soft tissue sarcomas in both adults and children, including Kaposi"s sarcoma, are published as well as preclinical and animal studies. This journal provides a central forum for the description of advances in diagnosis, assessment and treatment of this rarely seen, but often mismanaged, group of patients.
期刊最新文献
Oral Etoposide for Relapsed or Refractory Ewing Sarcoma in Adolescent and Adult Patients. Incidence of Undifferentiated Pleomorphic Sarcoma (UPS) in the United States. Desmoplastic Small Round Cell Tumors: Clinical Presentation, Molecular Characterization, and Therapeutic Approach of Seven Patients. ATRX and Its Prognostic Significance in Soft Tissue Sarcoma. Factors Influencing the Outcome of Patients with Primary Ewing Sarcoma of the Sacrum.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1