患者对体外受精和基因检测方案的看法和经验。

IF 3.1 Q1 OBSTETRICS & GYNECOLOGY Therapeutic advances in reproductive health Pub Date : 2020-04-16 eCollection Date: 2020-01-01 DOI:10.1177/2633494119899942
Erin Rothwell, Brandy Lamb, Erin Johnson, Shawn Gurtcheff, Naomi Riches, Melinda Fagan, Maya Sabatello, Erica Johnstone
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引用次数: 6

摘要

目的:体外受精过程中胚胎选择的决策和患者经验通常包括基因检测选项。本研究的目的是了解妇女使用体外受精和遗传技术的经验和观点。方法:对2016年7月至2017年7月期间接受体外受精、扩大携带者筛查并进行着床前非整倍体基因检测的女性患者进行访谈(n = 37)。采访被记录下来,并对记录进行了内容分析。结果:从数据分析中得出的分类包括意外结果、不确定性、未预料到的情感后果、过于强调女性的贡献以及对胚胎存活能力的质疑。患者在体外受精过程中使用基因技术的经历在这些结果中发挥了重要作用。结论:不孕不育在体外受精过程中的情绪和心理影响是参与者讨论的主要问题。未来的研究需要确定帮助管理意外结果和持续不确定性的方法,包括越来越多地使用基因技术,以避免增加不孕症的心理负担。有必要探索更多的支持选择或咨询服务的患者与不孕症在体外受精治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Patient perspectives and experiences with in vitro fertilization and genetic testing options.

Objective: Decision-making and patient experiences with embryo selection during in vitro fertilization often include genetic testing options. The purpose of this study was to gain insight about the experiences and perspectives of women using in vitro fertilization and genetic technologies.

Methods: Interviews (n = 37) were conducted among female patients who had undergone in vitro fertilization, underwent expanded carrier screening, and were offered pre-implantation genetic testing for aneuploidy between July 2016 and July 2017. The interviews were transcribed and a content analysis was conducted on the transcripts.

Results: Categories that emerged from the data analysis included unexpected outcomes, uncertainty, unanticipated emotional consequences, too much emphasis on the woman's contributions and questions about embryo viability. Patient experiences with genetic technologies during in vitro fertilization played a significant role within these results.

Conclusion: The emotional and psychological impacts of infertility during in vitro fertilization were the primary concerns discussed by participants. Future research is needed to identify ways to help manage unexpected outcomes and continuous uncertainty, including the increasing use of genetic technologies, to not add to the psychological burden of infertility. There is a need to explore more support options or counseling services for patients struggling with infertility during in vitro fertilization treatment.

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