Cyrus Tanade, Nathanael Pate, Elianna Paljug, Ryan A Hoffman, May D Wang
{"title":"埃博拉病毒传播的混合模型。","authors":"Cyrus Tanade, Nathanael Pate, Elianna Paljug, Ryan A Hoffman, May D Wang","doi":"10.1109/bibe.2019.00044","DOIUrl":null,"url":null,"abstract":"<p><p>The Ebola virus disease (EVD) epidemic that occurred in West Africa between 2014-16 resulted in over 28,000 cases and 11,000 deaths - one of the deadliest to date. A generalized model of the spatiotemporal progression of EVD for Liberia, Guinea, and Sierra Leone in 2014-16 remains elusive. There is also a disconnect in the literature on which interventions are most effective in curbing disease progression. To solve these two key issues, we designed a hybrid agent-based and compartmental model that switches from one paradigm to the other on a stochastic threshold. We modeled disease progression with promising accuracy using WHO datasets.</p>","PeriodicalId":87347,"journal":{"name":"Proceedings. IEEE International Symposium on Bioinformatics and Bioengineering","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/bibe.2019.00044","citationCount":"5","resultStr":"{\"title\":\"Hybrid Modeling of Ebola Propagation.\",\"authors\":\"Cyrus Tanade, Nathanael Pate, Elianna Paljug, Ryan A Hoffman, May D Wang\",\"doi\":\"10.1109/bibe.2019.00044\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The Ebola virus disease (EVD) epidemic that occurred in West Africa between 2014-16 resulted in over 28,000 cases and 11,000 deaths - one of the deadliest to date. A generalized model of the spatiotemporal progression of EVD for Liberia, Guinea, and Sierra Leone in 2014-16 remains elusive. There is also a disconnect in the literature on which interventions are most effective in curbing disease progression. To solve these two key issues, we designed a hybrid agent-based and compartmental model that switches from one paradigm to the other on a stochastic threshold. We modeled disease progression with promising accuracy using WHO datasets.</p>\",\"PeriodicalId\":87347,\"journal\":{\"name\":\"Proceedings. IEEE International Symposium on Bioinformatics and Bioengineering\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1109/bibe.2019.00044\",\"citationCount\":\"5\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings. IEEE International Symposium on Bioinformatics and Bioengineering\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/bibe.2019.00044\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2019/12/26 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings. IEEE International Symposium on Bioinformatics and Bioengineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/bibe.2019.00044","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2019/12/26 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
The Ebola virus disease (EVD) epidemic that occurred in West Africa between 2014-16 resulted in over 28,000 cases and 11,000 deaths - one of the deadliest to date. A generalized model of the spatiotemporal progression of EVD for Liberia, Guinea, and Sierra Leone in 2014-16 remains elusive. There is also a disconnect in the literature on which interventions are most effective in curbing disease progression. To solve these two key issues, we designed a hybrid agent-based and compartmental model that switches from one paradigm to the other on a stochastic threshold. We modeled disease progression with promising accuracy using WHO datasets.