3D-CRT能否满足胶质母细胞瘤靶区和OARs所需的剂量分布?三级癌症中心经验。

Q1 Medicine CNS Oncology Pub Date : 2020-09-01 Epub Date: 2020-09-18 DOI:10.2217/cns-2020-0010
Narendra Kumar, Srinivasa Gy, Chinna B Dracham, Treshita Dey, Renu Madan, Divya Khosla, Arun Oinum, Rakesh Kapoor
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引用次数: 0

摘要

目的:本研究的目的是对胶质母细胞瘤术后采用3d适形放射治疗,总剂量为60 Gy,分30份,计划靶体积和危险器官所接受的剂量进行剂量学分析。材料与方法:所有患者每天同时使用替莫唑胺,随后每月辅助使用替莫唑胺5天。结果:超过98%的患者接受60 Gy剂量的治疗。对正常全脑、肿瘤体积以及所有危险器官的剂量进行了分析。结论:考虑到胶质母细胞瘤的预后严重,尽管有最好的治疗方法,但其生存期有限,因此3d适形放疗是一种同样可接受的治疗选择。
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Can 3D-CRT meet the desired dose distribution to target and OARs in glioblastoma? A tertiary cancer center experience.

Aim: The purpose of the study is to perform a dosimetric analysis of the doses received by planning target volume and organ at risks in the postoperative glioblastoma by using 3D-conformal radiotherapy to a total dose of 60 Gy in 30 fractions. Materials & Methods: All patients received concurrent temozolomide every day, and this was followed by adjuvant temozolomide of 5 days of treatment per month. Results: More than 98% of patients were treated with a dose of 60 Gy. Doses were analyzed for the normal whole brain, tumor volume, as well as all the organs at risk. Conclusion: Given the grave prognosis and the limited survival of glioblastoma despite the best treatment available, makes 3D-conformal radiotherapy an equally acceptable treatment option.

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来源期刊
CNS Oncology
CNS Oncology Medicine-Neurology (clinical)
CiteScore
3.80
自引率
0.00%
发文量
12
审稿时长
13 weeks
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