欧洲生物库在 BBMRI-ERIC 框架下的重组:走向全球共享节点?

IF 3.1 Q1 Arts and Humanities Life Sciences, Society and Policy Pub Date : 2020-10-01 DOI:10.1186/s40504-020-00105-3
Violeta Argudo-Portal, Miquel Domènech
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引用次数: 0

摘要

存放生物样本的冷冻库后来成为生物银行,并于 2013 年在泛欧生物银行和生物分子资源研究基础设施-欧洲研究基础设施联盟(BBMRI-ERIC)下联网。通过对 BBMRI-ERIC 的文件分析,以及从科学和技术研究的角度对西班牙的生物银行家进行的多地点实地调查,我们探讨了在 BBMRI-ERIC 框架下生物银行有望做什么和成为什么,以及基础设施的转型如何促进生物银行实践的特定转变。欧洲生物库的主要目的是成为当代生物医学研究的中介(全球共享节点)和样本及其相关数据的分布式节点。我们认为,基础设施的过渡是复杂而多变的,会引起当地人对调整其做法以适应 BBMRI-ERIC 框架的关注,甚至会引起非成员的关注,西班牙的情况就说明了这一点,其收集和储存的 "旧做法 "受到了质疑。在本文中,我们旨在鼓励开展定性研究,探讨泛欧政策与前景、不同的背景解释以及生物银行重新配置之间的滞后性,并以此为契机探索滞后性的构成要素(例如,与 "旧有做法 "之间的紧张关系、与国家议程之间尚未解决的冲突、对地区生物银行可能集中化生物银行做法的保留意见、缺乏资金等)。此类研究不仅可以丰富政策指导,还可以丰富对技术科学基础设施可扩展性的认识。
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The reconfiguration of biobanks in Europe under the BBMRI-ERIC framework: towards global sharing nodes?

Freezers with biospecimen deposits became biobanks and later were networked at the pan-European level in 2013 under the Biobanking and BioMolecular Resources Research Infrastructure-European Research Infrastructure Consortium (BBMRI-ERIC). Drawing on document analysis about the BBMRI-ERIC and multi-sited fieldwork with biobankers in Spain from a science and technology studies approach, we explore what biobanks are expected to do and become under the BBMRI-ERIC framework, and how infrastructural transitions promote particular transformations in biobanking practices. The primary purpose of biobanks in Europe is presented as being to become mediators in contemporary biomedical research (global sharing nodes) distribution, and distributed nodes of samples and their associated data. We argue that infrastructural transitions are complicated and heterogeneous, giving rise to unattended local concerns on adjusting their practices to fit into the BBMRI-ERIC framework, even for non-members, as the case of Spain illustrates, where "old practices" of collection and storage are questioned. In this article, we aim to encourage qualitative studies to explore the lags between pan-European policies and prospects, different contextual interpretations, and biobanking reconfigurations as an opportunity to explore what that lag is made of (e.g. tensions with "old practices," unresolved conflicts with the national agendas, reservations on a possible centralization of the biobanking practices by regional biobanks, lack of funding, etc.). Such research could enrich not only policy guidance, but also the understanding of technoscientific infrastructures' scalability.

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来源期刊
Life Sciences, Society and Policy
Life Sciences, Society and Policy Arts and Humanities-Philosophy
自引率
0.00%
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0
审稿时长
18 weeks
期刊介绍: The purpose of Life Sciences, Society and Policy (LSSP) is to analyse social, ethical and legal dimensions of the most dynamic branches of life sciences and technologies, and to discuss ways to foster responsible innovation, sustainable development and user-driven social policies. LSSP provides an academic forum for engaged scholarship at the intersection of life sciences, philosophy, bioethics, science studies and policy research, and covers a broad area of inquiry both in emerging research areas such as genomics, bioinformatics, biophysics, molecular engineering, nanotechnology and synthetic biology, and in more applied fields such as translational medicine, food science, environmental science, climate studies, research on animals, sustainability, science education and others. The goal is to produce insights, tools and recommendations that are relevant not only for academic researchers and teachers, but also for civil society, policy makers and industry, as well as for professionals in education, health care and the media, thus contributing to better research practices, better policies, and a more sustainable global society.
期刊最新文献
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