[一家疗养院爆发由人类腺病毒血清 8 型引起的流行性角结膜炎]。

IF 0.9 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Revista Espanola De Salud Publica Pub Date : 2020-09-08
Óscar Esparcia Rodríguez, Angélica Gómez Martínez, María José Martínez Nieto, María Soledad Salmerón Cifuentes, Remedios Rodolfo Saavedra, Isidro de la Cruz de Julián
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引用次数: 0

摘要

目的:由人类腺病毒引起的眼部感染具有高度传染性,可导致疫情爆发,尤其是在养老院。在这项工作中,我们介绍了针对结膜炎疫情开展的流行病学和分析研究以及采取的控制措施:描述性流行病学研究。对症状出现日期早于官方通报的病例进行了回顾性分析。其余病例为前瞻性分析。采集结膜涂片进行微生物学研究。通过 PCR 和基因分型检测腺病毒,进行病毒学分析。设计了一份收集临床和流行病学信息的数据问卷。通过计算几率比(Odds Ratio)研究了与感染相关的可能风险因素:2019 年 6 月 11 日,阿尔瓦塞特省卫生厅流行病监测科接到通知,称一家老年病中心出现大量结膜炎病例。共发现 54 例病例:其中包括 43 名住院病人、3 名日托中心助理和 8 名工作人员。发病率分别为 35.8%、12.5% 和 8.4%。有三个风险因素与该疾病相关:病人缺乏自主能力、是疗养院的居民以及房间被分配在一楼。在患者样本中检测到人类腺病毒血清型8:结论:在内部居民中观察到的发病率很高,该疾病与患者缺乏自主性以及他们的房间被分配在疗养院的一楼有关。疫情是由人类腺病毒血清型8引起的。
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[Outbreak of epidemic keratoconjunctivitis caused by human adenovirus serotype 8 in a nursing home.]

Objective: Ocular infections caused by human adenovirus are highly contagious and can cause outbreaks, especially in nursing homes. In this work, we describe the epidemiological and analytical research as well as the control measures carried out for a conjunctivitis outbreak.

Methods: Descriptive epidemiological study. Cases with a symptom onset date prior to oficial communication were analyzed retrospectively. The rest was analyzed prospectively. Conjunctival smears were collected for microbiological study. Virological analysis was performed by detecting adenovirus by PCR and genotyping. A data questionnaire that collected clinical and epidemiological information was designed. Possible risk factors associated with infection were studied by calculating the Odds Ratio.

Results: On June 11, 2019, the Epidemiological Surveillance Section of the Provincial Health Department of Albacete was notified of the existence of a large number of cases of conjunctivitis in a geriatric center. 54 cases were declared: 43 internal residents, 3 day center assistants and 8 workers. Attack rates were 35.8%, 12.5% and 8.4% respectively. Three risk factors were associated with the disease: patient´s lack of autonomy, being a resident at the nursing home and having their room assigned on the first floor. Human adenovirus serotype 8 was detected in the patients' samples.

Conclusions: A high attack rate was observed in internal residents and the disease was associated with patient´s lack of autonomy and having their room assigned on the first floor of the nursing home. The outbreak was caused by human adenovirus serotype 8.

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来源期刊
Revista Espanola De Salud Publica
Revista Espanola De Salud Publica PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
2.00
自引率
0.00%
发文量
106
审稿时长
12 weeks
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