胃MALT淋巴瘤伴双克隆伽玛病并累及骨髓,模拟多发性骨髓瘤。

IF 0.4 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Puerto Rico Health Sciences Journal Pub Date : 2020-09-01
William Cáceres-Perkins, Fernando Cabanillas, Glorivette San Vicente, Carlos Rivera-Franceschini, Elías Sobrino-Najul, Laura I Vega-Vázquez, Daniel Conde-Sterling
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引用次数: 0

摘要

粘膜相关淋巴组织(MALT)淋巴瘤是一种b细胞肿瘤,通常影响胃肠道,通常是胃。在大多数情况下,结外边缘区淋巴瘤(ENMZL)是一种惰性疾病。伴副蛋白血症的MALT淋巴瘤常累及骨髓;这种参与推动了疾病的发展。在这里,我们报告了一例82岁的西班牙裔长期ENMZL患者,其胃部位对抗生素治疗和幽门螺杆菌根除有反应,但疾病多年来进展,出现双克隆gammopathy和骨髓累及,伴有明显的浆细胞分化。鉴于此,我们建议对ENMZL患者进行常规的蛋白检测。
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Gastric MALT Lymphoma with Biclonal Gammopathy and Bone Marrow Involvement Mimicking Multiple Myeloma.

Mucosa-associated lymphoid tissue (MALT) lymphomas are B-cell neoplasms that commonly affect the gastrointestinal (GI) tract, usually the stomach. In most cases, extranodal marginal zone lymphoma (ENMZL) is an indolent disease. Bone marrow involvement is common with MALT lymphoma accompanied by paraproteinemia; such involvement impels disease progression. Here, we present the case of an 82-year-old Hispanic patient with long-standing ENMZL in whom the gastric site responded to antibiotic treatment and Helicobacter pylori eradication, but the disease progressed over the years, with a biclonal gammopathy and bone marrow involvement with marked plasmacytic differentiation. In view of this, we suggest the routine evaluation of paraprotein in patients with ENMZL.

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来源期刊
Puerto Rico Health Sciences Journal
Puerto Rico Health Sciences Journal PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
0.60
自引率
0.00%
发文量
34
审稿时长
>12 weeks
期刊介绍: The Puerto Rico Health Sciences Journal (PRHSJ) is the scientific journal of the University of Puerto Rico Medical Sciences Campus. It was founded in 1982 as a vehicle for the publication of reports on scientific research conducted in-campus, Puerto Rico and abroad. All published work is original and peer-reviewed. The PRHSJ is included in PubMed/Medline, SCOPUS, Latindex, EBSCO, SHERPA/RoMEO, Science Citation Index Expanded (SciSearch®) and Journal Citation Reports/Science Edition. All papers are published both online and in hard copy. From its beginning, the PRHSJ is being published regularly four times a year. The scope of the journal includes a range of medical, dental, public health, pharmaceutical and biosocial sciences research. The journal publishes full-length articles, brief reports, special articles, reviews, editorials, case reports, clinical images, and letters arising from published material.
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