William Cáceres-Perkins, Fernando Cabanillas, Glorivette San Vicente, Carlos Rivera-Franceschini, Elías Sobrino-Najul, Laura I Vega-Vázquez, Daniel Conde-Sterling
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Gastric MALT Lymphoma with Biclonal Gammopathy and Bone Marrow Involvement Mimicking Multiple Myeloma.
Mucosa-associated lymphoid tissue (MALT) lymphomas are B-cell neoplasms that commonly affect the gastrointestinal (GI) tract, usually the stomach. In most cases, extranodal marginal zone lymphoma (ENMZL) is an indolent disease. Bone marrow involvement is common with MALT lymphoma accompanied by paraproteinemia; such involvement impels disease progression. Here, we present the case of an 82-year-old Hispanic patient with long-standing ENMZL in whom the gastric site responded to antibiotic treatment and Helicobacter pylori eradication, but the disease progressed over the years, with a biclonal gammopathy and bone marrow involvement with marked plasmacytic differentiation. In view of this, we suggest the routine evaluation of paraprotein in patients with ENMZL.
期刊介绍:
The Puerto Rico Health Sciences Journal (PRHSJ) is the scientific journal of the University of Puerto Rico Medical Sciences Campus. It was founded in 1982 as a vehicle for the publication of reports on scientific research conducted in-campus, Puerto Rico and abroad. All published work is original and peer-reviewed. The PRHSJ is included in PubMed/Medline, SCOPUS, Latindex, EBSCO, SHERPA/RoMEO, Science Citation Index Expanded (SciSearch®) and Journal Citation Reports/Science Edition. All papers are published both online and in hard copy. From its beginning, the PRHSJ is being published regularly four times a year. The scope of the journal includes a range of medical, dental, public health, pharmaceutical and biosocial sciences research. The journal publishes full-length articles, brief reports, special articles, reviews, editorials, case reports, clinical images, and letters arising from published material.