药物使用障碍和暴力:与个别药物类别的关联。

IF 5.2 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Epidemiologic Reviews Pub Date : 2020-01-31 DOI:10.1093/epirev/mxaa006
Shaoling Zhong, Rongqin Yu, Seena Fazel
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引用次数: 21

摘要

我们进行了一项系统回顾,检查了个别药物类别与暴力结果之间的联系。我们根据系统评价和荟萃分析指南的首选报告项目,搜索了主要病例对照和队列调查,这些调查使用经过验证的临床标准报告了被诊断为药物使用障碍的个体中对他人的暴力风险。我们确定了1990-2019年期间发表的18项研究,报告了来自591,411名药物使用障碍患者的数据。我们报告了不同类别药物使用障碍中暴力风险的比值比与非药物使用障碍的比值比。我们发现,大多数药物类别的比值比在0.8到25.0之间,多种药物使用障碍患者的比值比通常更高。此外,我们通过亚组和元回归分析探讨了研究间异质性的来源。队列调查报告的暴力风险低于病例对照报告(优势比= 2.7(95%置信区间(CI): 2.1, 3.5) vs. 6.6 (95% CI: 5.1, 8.6)),当结果是任何暴力而不是亲密伴侣暴力时,关联更强(优势比= 5.7 (95% CI: 3.8, 8.6) vs. 1.7 (95% CI: 1.4, 2.1)),这与meta回归的结果一致。总的来说,这些发现突出了预防和治疗药物使用障碍对减少暴力风险和相关发病率的潜在影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Drug Use Disorders and Violence: Associations With Individual Drug Categories.

We conducted a systematic review that examined the link between individual drug categories and violent outcomes. We searched for primary case-control and cohort investigations that reported risk of violence against others among individuals diagnosed with drug use disorders using validated clinical criteria, following Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. We identified 18 studies published during 1990-2019, reporting data from 591,411 individuals with drug use disorders. We reported odds ratios of the violence risk in different categories of drug use disorders compared with those without. We found odds ratios ranging from 0.8 to 25.0 for most individual drug categories, with generally higher odds ratios among individuals with polydrug use disorders. In addition, we explored sources of between-study heterogeneity by subgroup and meta-regression analyses. Cohort investigations reported a lower risk of violence than case-control reports (odds ratio =  2.7 (95% confidence interval (CI): 2.1, 3.5) vs. 6.6 (95% CI: 5.1, 8.6)), and associations were stronger when the outcome was any violence rather than intimate partner violence (odds ratio = 5.7 (95% CI: 3.8, 8.6) vs. 1.7 (95% CI: 1.4, 2.1)), which was consistent with results from the meta-regression. Overall, these findings highlight the potential impact of preventing and treating drug use disorders on reducing violence risk and associated morbidities.

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来源期刊
Epidemiologic Reviews
Epidemiologic Reviews 医学-公共卫生、环境卫生与职业卫生
CiteScore
8.10
自引率
0.00%
发文量
10
期刊介绍: Epidemiologic Reviews is a leading review journal in public health. Published once a year, issues collect review articles on a particular subject. Recent issues have focused on The Obesity Epidemic, Epidemiologic Research on Health Disparities, and Epidemiologic Approaches to Global Health.
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