Elshaddai Ephrem, Erica Gleason, Kelly Maurer, Kathleen E Sullivan
{"title":"通过使用引人入胜的现实生活调查评估遗传和遗传变异的理解。","authors":"Elshaddai Ephrem, Erica Gleason, Kelly Maurer, Kathleen E Sullivan","doi":"10.1159/000512086","DOIUrl":null,"url":null,"abstract":"<p><strong>Aims: </strong>This study was undertaken to examine how a layperson is likely to interpret genetic information delivered in a clinical setting.</p><p><strong>Methods: </strong>A novel survey was designed to engage the reader in a simulated discussion of heritability as it might relate to human disease. The survey took approximately 5 min to administer. 307 individuals of different backgrounds completed the survey in the outpatient waiting room on their cell phone.</p><p><strong>Results: </strong>Overall, basic knowledge of inheritance and the concepts of heredity scored very well in the study cohort. Both knowledge and interpretation questions were answered correctly more often than not. There was generally no association between the scores on survey and gender or age.</p><p><strong>Conclusions: </strong>People recognize the basic concepts of heritability but struggle with real-life interpretations and more nuanced concepts of heredity.</p>","PeriodicalId":49650,"journal":{"name":"Public Health Genomics","volume":"23 5-6","pages":"246-251"},"PeriodicalIF":1.3000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000512086","citationCount":"0","resultStr":"{\"title\":\"Understanding of Inheritance and Genetic Variation Assessed through the Use of an Engaging Real-Life Survey.\",\"authors\":\"Elshaddai Ephrem, Erica Gleason, Kelly Maurer, Kathleen E Sullivan\",\"doi\":\"10.1159/000512086\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aims: </strong>This study was undertaken to examine how a layperson is likely to interpret genetic information delivered in a clinical setting.</p><p><strong>Methods: </strong>A novel survey was designed to engage the reader in a simulated discussion of heritability as it might relate to human disease. The survey took approximately 5 min to administer. 307 individuals of different backgrounds completed the survey in the outpatient waiting room on their cell phone.</p><p><strong>Results: </strong>Overall, basic knowledge of inheritance and the concepts of heredity scored very well in the study cohort. Both knowledge and interpretation questions were answered correctly more often than not. There was generally no association between the scores on survey and gender or age.</p><p><strong>Conclusions: </strong>People recognize the basic concepts of heritability but struggle with real-life interpretations and more nuanced concepts of heredity.</p>\",\"PeriodicalId\":49650,\"journal\":{\"name\":\"Public Health Genomics\",\"volume\":\"23 5-6\",\"pages\":\"246-251\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2020-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1159/000512086\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Public Health Genomics\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1159/000512086\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2020/12/8 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"GENETICS & HEREDITY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Public Health Genomics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1159/000512086","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2020/12/8 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"GENETICS & HEREDITY","Score":null,"Total":0}
Understanding of Inheritance and Genetic Variation Assessed through the Use of an Engaging Real-Life Survey.
Aims: This study was undertaken to examine how a layperson is likely to interpret genetic information delivered in a clinical setting.
Methods: A novel survey was designed to engage the reader in a simulated discussion of heritability as it might relate to human disease. The survey took approximately 5 min to administer. 307 individuals of different backgrounds completed the survey in the outpatient waiting room on their cell phone.
Results: Overall, basic knowledge of inheritance and the concepts of heredity scored very well in the study cohort. Both knowledge and interpretation questions were answered correctly more often than not. There was generally no association between the scores on survey and gender or age.
Conclusions: People recognize the basic concepts of heritability but struggle with real-life interpretations and more nuanced concepts of heredity.
期刊介绍：
''Public Health Genomics'' is the leading international journal focusing on the timely translation of genome-based knowledge and technologies into public health, health policies, and healthcare as a whole. This peer-reviewed journal is a bimonthly forum featuring original papers, reviews, short communications, and policy statements. It is supplemented by topic-specific issues providing a comprehensive, holistic and ''all-inclusive'' picture of the chosen subject. Multidisciplinary in scope, it combines theoretical and empirical work from a range of disciplines, notably public health, molecular and medical sciences, the humanities and social sciences. In so doing, it also takes into account rapid scientific advances from fields such as systems biology, microbiomics, epigenomics or information and communication technologies as well as the hight potential of ''big data'' for public health.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
