撒哈拉以南非洲快速诊断检测的使用:对艾滋病毒预防的挑战和影响。

International Journal of MCH and AIDS Pub Date : 2021-01-01 Epub Date: 2020-12-30 DOI:10.21106/ijma.423
Elizabeth Armstrong-Mensah, Ato Kwamena Tetteh, Seung Choi
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引用次数: 1

摘要

人类免疫缺陷病毒(艾滋病毒)仍然是对全球健康的威胁。为了预防和控制由病毒引起的疾病,发达国家和发展中国家继续在研究和设备方面投入大量资金,以便准确检测病毒。在高负担国家,特别是撒哈拉以南非洲国家,使用高度敏感和有效的快速诊断测试有可能发现艾滋病毒。然而,在SSA,与HIV- rdt结果不准确、HIV误诊、检测能力差以及HIV- rdt试剂盒储存不当相关的挑战对效益产生了负面影响,并有可能破坏HIV预防。本文重点介绍了rdt在SSA地区HIV诊断中的应用、HIV- rdt挑战以及HIV- rdt挑战对HIV预防的影响。在回顾现有文献后,作者发现,尽管HIV- rdts由于HIV假阳性诊断的可能性而可能对SSA的HIV预防工作产生负面影响,但它们通常为资源贫乏环境中的人们提供快速结果,并且不要求他们返回检测地点获得结果。获得准确的快速艾滋病毒检测结果意味着检测呈阳性的人可以立即寻求治疗并采取措施防止病毒的未来传播。
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Utilization of Rapid Diagnostic Testing in sub-Saharan Africa: Challenges and Effects on HIV Prevention.

The human immunodeficiency virus (HIV) remains a global threat to health. To prevent and control the disease caused by the virus, developed and developing countries continue to invest heavily in research and equipment so as to accurately detect the virus. The utilization of highly sensitive and effective rapid diagnostic tests (RDTs) have the potential to detect HIV in high-burden countries, especially those in sub-Saharan Africa (SSA). Yet, in SSA, challenges associated with HIV-RDT result inaccuracy, HIV misdiagnosis, poor tester capacity, and the improper storage of HIV-RDT kits have negatively impacted the benefits, and threaten to undermine HIV prevention. This paper focuses on the utilization of RDTs in HIV diagnosis in SSA, HIV-RDT challenges, and the effects of HIV-RDT challenges on HIV prevention. Subsequent to reviewing available literature, the authors found that although HIV-RDTs can negatively impact HIV-prevention efforts in SSA due to the likelihood of false positive HIV diagnoses, they generally provide quick results for people in resource poor settings, and do not require them to return to the testing sites to obtain their results. Obtaining accurate rapid HIV results means people who test positive can immediately seek care and take steps to prevent future transmission of the virus.

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