【小肾细胞癌伴巨大骶骨转移1例】。

Q4 Medicine Japanese Journal of Urology Pub Date : 2020-01-01 DOI:10.5980/jpnjurol.111.48
Teruki Shimizu, Natsumi Takigami, Yuki Harada, Kenji Kawabata, Atsushi Ochiai
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引用次数: 0

摘要

一名66岁的男子因臀部疼痛和间歇性跛行去看附近的医生。磁共振成像显示他的骶骨有一个直径8厘米的肿瘤。他被转介到我们医院。腹部增强计算机断层扫描显示左肾有直径2.5 cm的小肿块,经肿瘤穿刺活检诊断为转移性骨病。然而,肾肿瘤的穿刺活检显示没有恶性肿瘤的证据。由于他拒绝进一步检查,我们开始使用酪氨酸激酶抑制剂舒尼替尼治疗。然而,它对他的骶骨转移几乎没有影响,他出现了两次大出血。结肠镜检查发现从骶骨转移到直肠后侧的广泛侵犯。患者在引入舒尼替尼2个月后死亡。最终病理解剖诊断为肾细胞癌伴骶骨转移。
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[SMALL RENAL CELL CARCINOMA PRESENTING WITH HUGE SACRALMETASTASIS: A CASE REPORT].

A 66-year-old man with buttock pain and intermittent claudication visited a nearby doctor. Magnetic resonance imaging revealed a tumor of 8 cm in diameter in his sacrum. He was referred to our hospital. Abdominal contrast enhanced computed tomography revealed a small mass of 2.5 cm in diameter on his left kidney and he was diagnosed with metastatic bone disease after needle tumor biopsy. However, needle biopsy of the renal tumor demonstrated no evidence of malignancy. As he rejected further examination, we started treatment using the tyrosine kinase inhibitor sunitinib. However, it had little effect on his sacral metastasis and he developed massive bowel bleeding twice. Extensive invasion from the sacral metastasis to the back side of the rectum was found on colonoscopy. The patient died 2 months after the introduction of sunitinib. The final diagnosis based on pathological autopsy was renal cell carcinoma with sacral metastasis.

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来源期刊
Japanese Journal of Urology
Japanese Journal of Urology Medicine-Urology
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