不断变化的基因组景观中的非模式生物研究。

Pub Date : 2019-04-01 DOI:10.21608/puj.2019.6449.1026
Monika Gulia-Nuss
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引用次数: 2

摘要

据估计,地球上大约有1000万种植物和动物,而只有大约150万种被记录在《生命目录》中。然而,我们对生物化学、分子、遗传学和细胞过程的知识来自于对不到12种生物体的研究。虽然我们对这些“模式”生物的研究取得了成效,但缺点是我们对绝大多数生物的生物学知之甚少,非模式生物。非模式生物是没有被研究界选择进行广泛研究的生物,主要是因为它们缺乏使模式生物易于研究的特征,例如它们不能在实验室中生长,生命周期长,繁殖力低或遗传不良。
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Non-model organism research in the changing genomic landscape.

It is estimated that the planet earth is host to approximately ten million species of plants and animals with only approximately 1.5 million documented in the Catalogue of Life. However, our knowledge of biochemical, molecular, genetics, and cellular processes comes from the studies of fewer than a dozen organisms. Although focusing our research on these "model" organisms has paid off, the downside is that we know very little about the biology of the vast majority of organisms, the non-model organisms. Non-model organisms are organisms that have not been selected by the research community for extensive study mostly because they lack the features that make model organisms easy to investigate e.g. they cannot grow in the laboratory, have a long life cycle, low fecundity or poor genetics.

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