自发性细菌性腹膜炎:诊断和治疗的最新进展。

IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Romanian Journal of Internal Medicine Pub Date : 2021-11-20 Print Date: 2021-12-01 DOI:10.2478/rjim-2021-0024
Roxana-Emanuela Popoiag, Carmen Fierbințeanu-Braticevici
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引用次数: 3

摘要

自发性细菌性腹膜炎(SBP)是肝硬化患者常见的并发症,死亡率增高。因此,所有有腹水且临床特征有较高诊断怀疑的患者均应行诊断性穿刺。尽管在鉴定血清或腹水的新诊断标记方面有大量的文献资料,但它们尚未得到验证。最终诊断需要分析腹水和腹水中存在> 250mm3的中性粒细胞多形核(PMN)。如果以前的数据表明,鉴定出的最常见微生物以革兰氏阴性菌为代表,那么我们目前面临的是革兰氏阳性菌和耐多药菌的增加。虽然需要及时和有效的治疗来预防结果,但这变得具有挑战性,因为一线治疗可能无效,导致预后恶化和住院死亡率增加。在本文中,我们将简要回顾现有资料的诊断和治疗收缩压。
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Spontaneous bacterial peritonitis: update on diagnosis and treatment.

Spontaneous bacterial peritonitis (SBP) is a common complication in patients with liver cirrhosis, with an increased risk of mortality. For this reason, a diagnostic paracentesis should be performed in all patients with ascites and clinical features with high diagnostic suspicion. Although literature data abound in identifying new diagnostic markers in serum or ascites, they have not yet been validated. The final diagnosis requires the analysis of ascites and the presence of > 250 mm3 neutrophil polymorphonuclear (PMN) in ascites. If previous data showed that the most common microorganisms identified were represented by gram-negative bacteria, we are currently facing an increase in gram-positive bacteria and multidrug-resistant bacteria. Although prompt and effective treatment is required to prevent outcomes, this becomes challenging as first-line therapies may become ineffective leading to worsening prognosis and increased in-hospital mortality. In this paper we will make a brief review of existing data on the diagnosis and treatment of SBP.

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来源期刊
Romanian Journal of Internal Medicine
Romanian Journal of Internal Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
3.20
自引率
5.30%
发文量
35
审稿时长
15 weeks
期刊介绍: Romanian Journal of Physics is a journal publishing physics contributions on the following themes: •Theoretical Physics & Applied Mathematics •Nuclear Physics •Solid State Physics & Materials Science •Statistical Physics & Quantum Mechanics •Optics •Spectroscopy •Plasma & Lasers •Nuclear & Elementary Particles Physics •Atomic and Molecular Physics •Astrophysics •Atmosphere and Earth Science •Environment Protection
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