一步一步:处理肝硬化的并发症。

IF 2.6 Q2 GASTROENTEROLOGY & HEPATOLOGY Hepatic Medicine : Evidence and Research Pub Date : 2021-05-25 eCollection Date: 2021-01-01 DOI:10.2147/HMER.S278032

Irene C Perez, Fabian J Bolte, William Bigelow, Zachary Dickson, Neeral L Shah

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引用次数: 6

摘要

根据疾病控制和预防中心的数据，慢性肝病和肝硬化是美国第11大死因。慢性肝病的常见病因包括酒精、病毒性肝炎和非酒精性脂肪性肝炎(NASH)。炎症是肝病发展为肝纤维化和最终肝硬化的关键驱动因素。虽然慢性肝病的严重程度持续延长，但治疗更容易区分代偿性肝硬化和失代偿性肝硬化。在这篇综述中，我们在文献综述和美国肝病研究协会(AASLD)现行临床实践指南的基础上，讨论肝硬化常见并发症的病理生理、临床特征和处理。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Step by Step: Managing the Complications of Cirrhosis.

According to the Centers for Disease Control and Prevention, chronic liver disease and cirrhosis is the 11th leading cause of death in the United States. Common causes of chronic liver disease include alcohol, viral hepatitis, and non-alcoholic steatohepatitis (NASH). Inflammation is a critical driver in the progression of liver disease to liver fibrosis and ultimately cirrhosis. While the severity of chronic liver disease extends over a continuum, the management is more easily differentiated between compensated and decompensated cirrhosis. In this review, we discuss pathophysiology, clinical features and management of common complications of liver cirrhosis based on literature review and the current clinical practice guidelines of the American Association for the Study of Liver Diseases (AASLD).

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来源期刊

Hepatic Medicine : Evidence and Research GASTROENTEROLOGY & HEPATOLOGY-

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0.00%

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审稿时长

16 weeks

期刊介绍： Hepatic Medicine: Evidence and Research is an international, peer-reviewed, open access, online journal. Publishing original research, reports, editorials, reviews and commentaries on all aspects of adult and pediatric hepatology in the clinic and laboratory including the following topics: Pathology, pathophysiology of hepatic disease Investigation and treatment of hepatic disease Pharmacology of drugs used for the treatment of hepatic disease Although the main focus of the journal is to publish research and clinical results in humans; preclinical, animal and in vitro studies will be published where they will shed light on disease processes and potential new therapies. Issues of patient safety and quality of care will also be considered. As of 1st April 2019, Hepatic Medicine: Evidence and Research will no longer consider meta-analyses for publication.