比美珠单抗治疗中重度斑块性银屑病。

Q1 Medicine Skin therapy letter Pub Date : 2021-05-01

Ryan D Gotesman, Ron Vender

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摘要

牛皮癣是一种免疫介导的炎症性皮肤病，影响约2%的人口，并与许多合并症有关。最近的研究表明，白细胞介素-17信号在银屑病的发病机制中起着至关重要的作用。Bimekizumab是一种新型单克隆抗体治疗银屑病，使用单一结合位点抑制IL-17A和IL-17F。在这里，我们将讨论比美珠单抗治疗中重度斑块型银屑病的安全性和有效性。

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Bimekizumab for Moderate-to-Severe Plaque Psoriasis.

Psoriasis is an immune-mediated inflammatory skin disease that affects about 2% of the population and is associated with many comorbidities. Recent advances have demonstrated interleukin (IL)-17 signaling plays a crucial role in the pathogenesis of psoriasis. Bimekizumab is a novel monoclonal antibody treatment for psoriasis that uses a single binding site to inhibit IL-17A and IL-17F. Here we will discuss the safety and efficacy of bimekizumab in the treatment of moderate-to-severe plaque psoriasis.

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