利用聚类分析确定平均每日饮酒量的性别分布:是否存在酒精依赖人群的单独分布?

IF 3.2 2区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Population Health Metrics Pub Date : 2021-06-07 DOI:10.1186/s12963-021-00261-4
Huan Jiang, Shannon Lange, Alexander Tran, Sameer Imtiaz, Jürgen Rehm
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引用次数: 3

摘要

背景:目前尚不清楚酒精使用障碍(AUDs)是否可以用平均每日饮酒量的特定水平来表征。本研究的目的是利用各种聚类技术,对饮酒者和酒精依赖者(最严重的AUD)的平均每日酒精消费量分布进行建模。方法:本分析采用全国酒精及相关疾病流行病学调查第1和第2期数据。应用聚类算法对代表平均每日饮酒量的一组数据点进行分组。然后使用高斯混合模型(gmm)来估计属于混合分布之一的数据点的可能性。个体被分配到GMMs后验概率最高的组,并对每个组的治疗利用率进行检查。结果:通过聚类技术建立酒精消耗模型是可行的。所确定的集群并没有将酒精依赖作为一个以更高水平的酒精消费为特征的单独集群。在有酒精依赖的女性和男性中,每日饮酒量相对较低。结论:总的来说,我们发现很少有证据表明具有相同饮酒分布的人群聚集,这可能与目前定义的酒精使用障碍患者具有临床相关性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Determining the sex-specific distributions of average daily alcohol consumption using cluster analysis: is there a separate distribution for people with alcohol dependence?

Background: It remains unclear whether alcohol use disorders (AUDs) can be characterized by specific levels of average daily alcohol consumption. The aim of the current study was to model the distributions of average daily alcohol consumption among those who consume alcohol and those with alcohol dependence, the most severe AUD, using various clustering techniques.

Methods: Data from Wave 1 and Wave 2 of the National Epidemiologic Survey on Alcohol and Related Conditions were used in the current analyses. Clustering algorithms were applied in order to group a set of data points that represent the average daily amount of alcohol consumed. Gaussian Mixture Models (GMMs) were then used to estimate the likelihood of a data point belonging to one of the mixture distributions. Individuals were assigned to the clusters which had the highest posterior probabilities from the GMMs, and their treatment utilization rate was examined for each of the clusters.

Results: Modeling alcohol consumption via clustering techniques was feasible. The clusters identified did not point to alcohol dependence as a separate cluster characterized by a higher level of alcohol consumption. Among both females and males with alcohol dependence, daily alcohol consumption was relatively low.

Conclusions: Overall, we found little evidence for clusters of people with the same drinking distribution, which could be characterized as clinically relevant for people with alcohol use disorders as currently defined.

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来源期刊
Population Health Metrics
Population Health Metrics PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
6.50
自引率
0.00%
发文量
21
审稿时长
29 weeks
期刊介绍: Population Health Metrics aims to advance the science of population health assessment, and welcomes papers relating to concepts, methods, ethics, applications, and summary measures of population health. The journal provides a unique platform for population health researchers to share their findings with the global community. We seek research that addresses the communication of population health measures and policy implications to stakeholders; this includes papers related to burden estimation and risk assessment, and research addressing population health across the full range of development. Population Health Metrics covers a broad range of topics encompassing health state measurement and valuation, summary measures of population health, descriptive epidemiology at the population level, burden of disease and injury analysis, disease and risk factor modeling for populations, and comparative assessment of risks to health at the population level. The journal is also interested in how to use and communicate indicators of population health to reduce disease burden, and the approaches for translating from indicators of population health to health-advancing actions. As a cross-cutting topic of importance, we are particularly interested in inequalities in population health and their measurement.
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