短期脊髓电刺激对带状疱疹后遗神经痛患者的影响及其对睡眠质量的影响。

IF 0.6 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Neuro endocrinology letters Pub Date : 2021-05-04
Jinzhou Liu, Aimin Zhang, Xiaolong Ye, Xin H, Ruilin He, Zongbin Jiang
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引用次数: 0

摘要

摘要材料与方法:将160例急性PHN患者按随机数字表法分为对照组和实验组,各80例。实验组植入经皮硬膜外电极,给予短期脊髓电刺激治疗,对照组给予神经阻滞治疗,比较两组患者不同时期的疗效和睡眠质量。疼痛视觉模拟量表(VAS)评分和匹兹堡睡眠质量指数(PSQI)分别用于评估镇痛效果和睡眠质量:结果:实验组患者在治疗后1、2、3 d、1周、1和3个月的视觉模拟量表(VAS)评分和匹兹堡睡眠质量指数(PSQI)评分均明显低于对照组[治疗后3个月:(0.86±0.31)分至(2.97±0.55)分,(5.4±1.16)分至(7.46±1.27)分],差异有统计学意义(两组均为PConclusion:短期脊髓电刺激对 PHN 的临床效果良好,能够对患者的疼痛起到快速有效的缓解作用。同时,还能有效改善患者的睡眠质量,安全性高。
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The effect of short-term spinal cord electrical stimulation on patients with postherpetic neuralgia and its effect on sleep quality.

Objectives: To investigate the effect of short-term spinal cord electrical stimulation (stSCS) on postherpetic neuralgia (PHN) and its effect on sleep quality in patients in Guangxi, China.

Material and methods: 160 patients with acute PHN patients were divided into a control group and an experimental group according to the random number table method, 80 cases each. The experimental group was implanted with percutaneous epidural electrodes and given short-term spinal cord electrical stimulation treatment, while the control group was treated with nerve block therapy to compare the efficacy and sleep quality of the two groups of patients in different periods. Pain Visual Analogue Scale (VAS) score and Pittsburgh Sleep Quality Index (PSQI) were used to evaluate the analgesic effect and sleep quality, respectively.

Results: The patients in the experimental group had significantly lower visual analog scale (VAS) scores and Pittsburgh Sleep Quality Index (PSQI) scores at 1, 2, 3 d, 1 week, and 1 and 3 months after treatment than those in the control group [after treatment 3 months: (0.86±0.31) points to (2.97±0.55) points, (5.4±1.16) score to (7.46±1.27) score], the difference was statistically significant (both P<0.05), and VAS and PSQI scores of the two groups showed a significant downward trend with the increase of treatment time.

Conclusion: The clinical effect of short-term spinal cord electrical stimulation on PHN is good, and it can play a rapid and effective relief effect on pain in patients. At the same time, it will effectively improve patient's sleep quality, with high safety.

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来源期刊
Neuro endocrinology letters
Neuro endocrinology letters 医学-内分泌学与代谢
CiteScore
1.00
自引率
14.30%
发文量
24
审稿时长
6 months
期刊介绍: Neuroendocrinology Letters is an international, peer-reviewed interdisciplinary journal covering the fields of Neuroendocrinology, Neuroscience, Neurophysiology, Neuropsychopharmacology, Psycho­neu­ro­immunology, Reproductive Medicine, Chro­no­biology, Human Ethology and re­lated fields for RAPID publication of Original Papers, Review Articles, State-of-the-art, Clinical Reports and other contributions from all the fields covered by Neuroendocrinology Letters. Papers from both basic research (methodology, molecular and cellular biology, anatomy, histology, biology, embryology, teratology, normal and pathological physiology, biophysics, pharmacology, pathology and experimental pathology, biochemistry, neurochemistry, enzymology, chronobiology, receptor studies, endocrinology, immunology and neuroimmunology, animal phy­siology, animal breeding and ethology, human ethology, psychology and others) and from clinical research (neurology, psychiatry and child psychiatry, obstetrics and gynecology, pediatrics, endocrinology, immunology, cardiovascular studies, internal medicine, oncology and others) will be considered. The Journal publishes Original papers and Review Articles. Brief reports, Special Communications, proved they are based on adequate experimental evidence, Clinical Studies, Case Reports, Commentaries, Discussions, Letters to the Editor (correspondence column), Book Reviews, Congress Reports and other categories of articles (philosophy, art, social issues, medical and health policies, biomedical history, etc.) will be taken under consideration.
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