泪膜动态与眨眼和隐形眼镜运动

Daniel M Anderson;Maria Corsaro;Jonathan Horton;Tim Reid;Padmanabhan Seshaiyer
{"title":"泪膜动态与眨眼和隐形眼镜运动","authors":"Daniel M Anderson;Maria Corsaro;Jonathan Horton;Tim Reid;Padmanabhan Seshaiyer","doi":"10.1093/imammb/dqab010","DOIUrl":null,"url":null,"abstract":"We develop a lubrication theory-based mathematical model that describes the dynamics of a tear film during blinking and contact lens (CL) wear. The model extends previous work on pre-corneal tear film dynamics during blinking by coupling the partial differential equation for tear film thickness to a dynamic model for CL motion. We explore different models for eyelid motion and also account for possible voluntary and involuntary globe (eyeball) rotation that may accompany blinking. Boundary conditions for mass flux at the eyelids are also adapted to account for the presence and motion of the CL. Our predictions for CL motion compare reasonably with existing data. Away from the eyelids the pre-lens tear film (PrLTF) is shifted, relative to its pre-corneal counterpart, in the direction of CL motion. Near the eyelids, the inflow/outflow of fluid under the eyelids also influences the PrLTF profile. We also compare our PrLTF dynamics to existing in vivo tear film thickness measurements.","PeriodicalId":94130,"journal":{"name":"Mathematical medicine and biology : a journal of the IMA","volume":"38 3","pages":"355-395"},"PeriodicalIF":0.0000,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Tear film dynamics with blinking and contact lens motion\",\"authors\":\"Daniel M Anderson;Maria Corsaro;Jonathan Horton;Tim Reid;Padmanabhan Seshaiyer\",\"doi\":\"10.1093/imammb/dqab010\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We develop a lubrication theory-based mathematical model that describes the dynamics of a tear film during blinking and contact lens (CL) wear. The model extends previous work on pre-corneal tear film dynamics during blinking by coupling the partial differential equation for tear film thickness to a dynamic model for CL motion. We explore different models for eyelid motion and also account for possible voluntary and involuntary globe (eyeball) rotation that may accompany blinking. Boundary conditions for mass flux at the eyelids are also adapted to account for the presence and motion of the CL. Our predictions for CL motion compare reasonably with existing data. Away from the eyelids the pre-lens tear film (PrLTF) is shifted, relative to its pre-corneal counterpart, in the direction of CL motion. Near the eyelids, the inflow/outflow of fluid under the eyelids also influences the PrLTF profile. We also compare our PrLTF dynamics to existing in vivo tear film thickness measurements.\",\"PeriodicalId\":94130,\"journal\":{\"name\":\"Mathematical medicine and biology : a journal of the IMA\",\"volume\":\"38 3\",\"pages\":\"355-395\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Mathematical medicine and biology : a journal of the IMA\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://ieeexplore.ieee.org/document/9579101/\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Mathematical medicine and biology : a journal of the IMA","FirstCategoryId":"1085","ListUrlMain":"https://ieeexplore.ieee.org/document/9579101/","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1

摘要

我们开发了一个基于润滑理论的数学模型,描述了眨眼和隐形眼镜(CL)佩戴过程中泪膜的动力学。该模型通过将泪膜厚度的偏微分方程与CL运动的动力学模型相耦合,扩展了先前关于眨眼过程中角膜前泪膜动力学的工作。我们探索了眼睑运动的不同模型,并解释了可能伴随眨眼的眼球旋转。眼睑处质量通量的边界条件也适用于CL的存在和运动。我们对CL运动的预测与现有数据比较合理。晶状体前泪膜(PrLTF)相对于角膜前泪膜在CL运动方向上移动,远离眼睑。在眼睑附近,眼睑下方流体的流入/流出也会影响PrLTF轮廓。我们还将我们的PrLTF动力学与现有的体内泪膜厚度测量进行了比较。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Tear film dynamics with blinking and contact lens motion
We develop a lubrication theory-based mathematical model that describes the dynamics of a tear film during blinking and contact lens (CL) wear. The model extends previous work on pre-corneal tear film dynamics during blinking by coupling the partial differential equation for tear film thickness to a dynamic model for CL motion. We explore different models for eyelid motion and also account for possible voluntary and involuntary globe (eyeball) rotation that may accompany blinking. Boundary conditions for mass flux at the eyelids are also adapted to account for the presence and motion of the CL. Our predictions for CL motion compare reasonably with existing data. Away from the eyelids the pre-lens tear film (PrLTF) is shifted, relative to its pre-corneal counterpart, in the direction of CL motion. Near the eyelids, the inflow/outflow of fluid under the eyelids also influences the PrLTF profile. We also compare our PrLTF dynamics to existing in vivo tear film thickness measurements.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Mathematical modeling and analysis of emission and mitigation of methane from the integrated rice-livestock farming system. A signal processing tool adapted to the periodic biphasic phenomena: the Dynalet transform. Modelling the influence of vitamin D and probiotic supplementation on the microbiome and immune response. Effect of diffusivity of amyloid beta monomers on the formation of senile plaques. Genesis of intimal thickening due to hemodynamical shear stresses.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1