退行性关节疾病患者的颞下颌关节穿刺:10至22年随访。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2021-02-01 DOI:10.11607/ofph.2871
Luca Guarda-Nardini, Maddalena Meneghini, Sayma Zegdene, Daniele Manfredini
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引用次数: 1

摘要

目的:通过长期(即10-22年)随访,报告颞下颌关节(TMJ)关节穿刺加增粘治疗退行性关节疾病(DJD)的有效性。方法:共103例患者,年龄在30 ~ 91岁之间(男性13例,女性90例;平均年龄63.7岁),这些患者在1998年至2010年期间接受了5次关节穿刺并补充HA粘胶剂以控制其与TMJ DJD相关的症状,并被召回进行临床评估。治疗周期结束后,根据以下参数评估临床结果:最大张嘴(MO)、功能性疼痛(PF)、静止疼痛(PR)和自我报告的咀嚼效率(CE)。根据先前的出版物,在基线(T0)和连续随访评估(至少3个月(T1)和1年(T2)后收集数据。在此之前接受治疗至少10年的患者被召回本研究(T3: 10至22年随访)。对重复测量进行方差分析以评估随时间的变化。结果:所有临床参数在T1时均有显著改善,并维持10年(T3),各参数P < 0.01。在T3时,56%的受试者认为治疗效果很好,26.5%的受试者认为治疗效果很好,10.7%的受试者认为有中度改善,6.8%的受试者认为有轻微改善或没有任何改善。只有7人在T2后需要额外治疗。结论:本研究结果表明,通过关节穿刺和补充黏液的循环治疗,短期或中期达到的TMJ DJD的症状管理可以长期有效地维持。
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Temporomandibular Joint Arthrocentesis in Patients with Degenerative Joint Disease: A 10- to 22-year Follow-up.

Aims: To report the effectiveness of temporomandibular joint (TMJ) arthrocentesis with viscosupplementation for degenerative joint disease (DJD) over a long-term (ie, 10-22 years) follow-up.

Methods: A total of 103 patients aged between 30 and 91 years (13 men and 90 women; mean age 63.7 years) who received a cycle of five arthrocentesis sessions with HA viscosupplementation to manage their symptoms related to TMJ DJD during the time period from 1998 to 2010 were recalled for clinical evaluation. After the treatment cycle, clinical outcomes were assessed based on the following parameters: maximum mouth opening (MO), pain with function (PF), pain at rest (PR), and self-reported chewing efficiency (CE). Data were collected at baseline (T0) and at successive follow-up assessments, after at least 3 months (T1) and 1 year (T2), as per previous publications. Patients who had received treatment at least 10 years prior were then recalled for this study (T3: 10 to 22 years follow-up). Analysis of variance for repeated measures was performed to assess changes over time.

Results: Significant improvement in all clinical parameters was achieved at T1 and was maintained for up to 10 years (T3), with P < .01 for each parameter. At T3, treatment effectiveness was perceived as excellent by 56% and as good by 26.5% of subjects, while 10.7% perceived a moderate improvement, and 6.8% referred a slight improvement or did not have any improvement. Only seven individuals required additional treatments after T2.

Conclusion: These findings suggest that the symptomatic management of TMJ DJD achieved in the short or medium term with a cycle of arthrocentesis and viscosupplementation was effectively maintained in the long term.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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