聚癸二酸甘油是一种新兴的生物医学用途聚酯:结构、性能和改性。

Q3 Medicine Polimery w medycynie Pub Date : 2021-01-01 DOI:10.17219/pim/139585
Paweł Piszko, Bartłomiej Kryszak, Aleksandra Piszko, Konrad Szustakiewicz
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引用次数: 16

摘要

聚甘油癸二酸酯(PGS)是一种脂肪族聚酯,近年来因其在生物医学组织工程方面的巨大应用潜力而引起了科学界的广泛关注。它在文献中以二维薄膜,多孔支架或非织造布的形式呈现,仅举几例。此外,还提出了作为复合材料或聚合物共混物的组分的各种应用。它的物理化学性质可以通过合成和合成后改性,包括交联或化学改性,如共聚显著调节。许多科学家都在讨论PGS作为生物医学应用的新一代聚合物。其再生潜力已被证实,特别是在软组织(包括神经、软骨和心脏组织)的组织工程中。因此,我们必须预见到PGS在当代生物医学应用中的重要性。这篇简短的综述旨在使读者熟悉这种用于组织工程的相对较新的高分子材料。
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Brief review on poly(glycerol sebacate) as an emerging polyester in biomedical application: Structure, properties and modifications.

Poly(glycerol sebacate) (PGS) is an aliphatic polyester which attracted significant scientific attention in recent years due to its vast potential in biomedical applications with regard to tissue engineering. It has been presented in the literature in the form of 2D films, porous scaffolds or nonwovens, to name just a few. Moreover, various applications have been proposed as a component of composite materials or polymer blends. Its physicochemical properties can be significantly adjusted by means of synthesis and post-synthetic modifications, including cross-linking or chemical modification, such as copolymerization. Many scientists have discussed PGS as a new-generation polymer for biomedical applications. Its regenerative potential has been confirmed, in particular, in tissue engineering of soft tissues (including nerve, cartilage and cardiac tissues). Therefore, we must anticipate a growing importance of PGS in contemporary biomedical applications. This brief review aims to familiarize the readers with this relatively new polymeric material for tissue engineering applications.

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来源期刊
Polimery w medycynie
Polimery w medycynie Medicine-Medicine (all)
CiteScore
3.30
自引率
0.00%
发文量
9
审稿时长
53 weeks
期刊最新文献
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