评估尿道狭窄尿道成形术中初级颊粘膜移植挛缩程度:一项在三级医疗中心的前瞻性观察研究。

IF 1.8 Q3 UROLOGY & NEPHROLOGY Advances in Urology Pub Date : 2021-07-23 eCollection Date: 2021-01-01 DOI:10.1155/2021/9913452
A BhalaguruIyyan, P Puvai Murugan, Chandranaath C Alakhananda, B M Zeeshan Hameed
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摘要

口腔粘膜移植尿道成形术被认为是治疗尿道狭窄疾病的金标准。BMG尿道成形术的成功率在66%到99%之间。其中一个可能的失败原因是BMG挛缩。原发性BMG挛缩率了解甚少,未见报道。本研究的目的是评估口腔粘膜在收获后立即挛缩的程度。材料与方法:本研究为2016年1月至2019年12月在我院泌尿外科开展的前瞻性观察性研究。所有首次行BMG尿道成形术的尿道狭窄疾病患者均在获得知情同意后纳入研究。记录了人口统计学和患者临床资料。根据术中尿道狭窄大小,在颊黏膜上标记取前移植物并计算其大小。从口腔中取出移植物后,立即测量移植物的采后未拉伸大小。采用配对t检验分析BMG大小的变化。结果:44例患者纳入研究。患者平均年龄53.6岁。平均狭窄长度为7.45 cm(范围4-12 cm)。采前和采后BMG平均尺寸分别为8.3 × 1.5 cm和7.6 × 1.3 cm。颊粘膜移植物的长度减少8.4%,宽度减少9.5%。结论:一期颊黏膜移植挛缩的长度约为8.4%,宽度约为9.5%。在采集颊粘膜时,最好标记得比必要的宽,以便进行无张力吻合。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Evaluation of the Extent of Primary Buccal Mucosal Graft Contracture in Augmentation Urethroplasty for Stricture Urethra: A Prospective Observational Study at a Tertiary Healthcare Centre.

Introduction: Buccal mucosal graft (BMG) urethroplasty is considered as gold standard in the treatment of urethral stricture disease. The successful outcome after BMG urethroplasty varies between 66 and 99%. One of the possible causes for failure is BMG contracture. Primary BMG contracture rate is poorly understood and unreported. The present study aimed to evaluate the extent of contracture of buccal mucosa immediately after harvesting.

Materials and methods: This was a prospective observational study conducted in the Department of Urology at our institute between January 2016 and December 2019. All patients with urethral stricture disease undergoing BMG urethroplasty for the first time were enrolled in the study after obtaining informed consent. Demographic and patient clinical profile was noted. Based on the intraoperative urethral stricture size, the preharvest graft was marked on the buccal mucosa and the size was calculated. Postharvest unstretched size of the graft was measured immediately after graft removal from the oral cavity. Alteration in BMG size was analysed using paired t-test.

Results: Forty-four patients were included in the study. Mean age of the patient was 53.6 years. Mean stricture length was 7.45 cm (range 4-12 cm). Mean pre- and postharvest BMG size was 8.3 × 1.5 cm and 7.6 × 1.3 cm, respectively. There was a 8.4% decrease in length and 9.5% decrease in width of the buccal mucosal graft.

Conclusion: Primary buccal mucosal graft contracture is around 8.4% in length and 9.5% in width. It would be better to mark wider than necessary while harvesting buccal mucosa so that tension-free anastomosis is performed.

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来源期刊
Advances in Urology
Advances in Urology UROLOGY & NEPHROLOGY-
CiteScore
2.90
自引率
0.00%
发文量
17
审稿时长
15 weeks
期刊介绍: Advances in Urology is a peer-reviewed, open access journal that publishes state-of-the-art reviews and original research papers of wide interest in all fields of urology. The journal strives to provide publication of important manuscripts to the widest possible audience worldwide, without the constraints of expensive, hard-to-access, traditional bound journals. Advances in Urology is designed to improve publication access of both well-established urologic scientists and less well-established writers, by allowing interested scientists worldwide to participate fully.
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