防变色系统:一种新型洗必泰漱口水。

IF 0.8 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Journal of biological regulators and homeostatic agents Pub Date : 2021-07-01 DOI:10.23812/21-4supp1-10
G Tetè, F Cattoni, E Polizzi
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引用次数: 9

摘要

氯己定被定义为具有生物相容性,这就是为什么它在开始牙科手术之前被用作患者的漱口水(2)。它能够很好地与牙齿和粘膜结合,并在12小时内释放,这就是为什么它被用于治疗牙龈炎和术后伤口愈合。氯己定的长期副作用是色素沉着。为了解决这个问题,随着时间的推移,人们尝试了各种类型的防变色剂。现在还有其他类型的防变色系统,例如,在我们的研究中,我们使用了一个包含称为SPPD的防变色系统的测试组。一项84例患者的单中心、前瞻性、双盲随机临床试验。所研究的治疗方法包括4种漱口水(CHX 0.12% SPDD无酒精;CHX 0.20% SPDD无酒精;CHX 0.12%不含ADS;CHX 0.20%酒精(不含ADS)。尽管该研究存在局限性,但所有测试的漱口水都显示出减少牙菌斑数量的良好功效。对比0.12%和0.20%的实验浓度,0.20%的氯己定浓度在PI和BI参数上略优于0.12%的等效浓度。SPDD是一个创新的防变色系统,给漱口水一个伟大的味道。
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Anti-discoloration system: a new chlorhexidine mouthwash.

Chlorhexidine is defined as biocompatible, which is why it is used as a mouthrinse for the patient before starting dental procedures (2). It has the ability to bind well to teeth and mucous membranes and is released for twelve hours, which is why it is used as a treatment for gingivitis and also in post-operative wound healing. The long-term side effects of chlorhexidine are pigmentations. To remedy this, various types of antidiscoloration have been tried out over time. Nowadays there are other types of anti-discoloration systems such as, for example, in our study we used a test group containing an anti-discoloration system called SPPD. A single-center, prospective, double-blind randomized clinical trial on 84 patients. The investigated treatments consisted of 4 mouthwashes (CHX 0.12% SPDD alcohol free; CHX 0.20% SPDD alcohol free; CHX 0.12% alcohol free with ADS; CHX 0.20% alcohol free with ADS). Despite the limitations of the study, all the mouthwashes tested showed good efficacy in reducing the amount of plaque. Comparing the two experimental concentrations (0.12% and 0.20%) tested here demonstrates that the 0.20% chlorhexidine concentration slightly surpasses its 0.12% equivalent with regard to the PI and BI parameters. The SPDD is an innovative anti-discoloration system and gives the mouthwash a great taste.

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来源期刊
CiteScore
2.20
自引率
15.60%
发文量
0
审稿时长
6 months
期刊介绍: Journal of Biological Regulators & Homeostatic Agents (IF 1.397) is a peer-reviewed journal published every 2 months. The journal publishes original papers describing research in the fields of experimental and clinical medicine, molecular biology, biochemistry, regulatory molecules, cellular immunology and pharmacology.
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