[经上皮PTK联合地形引导PRK治疗外伤性角膜瘢痕]。

4区 医学 Q3 Medicine Ophthalmologe Pub Date : 2022-03-01 Epub Date: 2021-08-25 DOI:10.1007/s00347-021-01480-8
Klemens Paul Kaiser, Elfriede Wissiak, Tom Müller, Loay Daas, Yosuf El-Shabrawi, Navid Ardjomand
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引用次数: 0

摘要

背景:角膜瘢痕可严重损害视力,治疗具有挑战性。该研究旨在评估一种有前途的微创选择,在治疗角膜疤痕使用经上皮地形引导消融。方法:本回顾性介入研究纳入2017年至2020年间4例因外伤出现角膜瘢痕和角膜表面不规则的患者的4只眼,并进行了地形引导光屈光性角膜切除术(TG-PRK)治疗。使用CRS-Master(蔡司,耶拿,德国)计算所有4例患者的消融剖面。主要观察指标为未矫正和最佳矫正的距离视力、明显屈光和角膜地形图的规律性。平均年龄34.75 ±15.39岁,随访时间6个月。结果:3例患者一次完成了完全的主观屈光矫正,1例患者屈光不正为+0.5 d。本例患者仅进行了角膜表面平滑,未进行额外的屈光矫正。4例患者未矫正(2-3斯奈伦线)和矫正(3斯奈伦线)的距离视力均有改善。治疗中、术后均无并发症发生,视力无下降。结论:在角膜瘢痕患者中应用TG-PRK可改善部分病例的视力。在近视患者中,大多数屈光不正也可以在一次治疗中矫正。
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[Combined transepithelial PTK and topography-guided PRK for treatment of trauma-related corneal scarring].

Background: Corneal scars can severely impair visual performance and treatment can be challenging. The study aimed to evaluate a promising minimally invasive option in the treatment of corneal scars using transepithelial topography-guided ablation.

Methods: This retrospective interventional study involved four eyes of four patients who developed corneal scarring and irregular surfaces due to trauma and were treated with topography-guided photorefractive keratectomy (TG-PRK) between 2017 and 2020. The ablation profile was calculated in all four cases using CRS-Master (Zeiss, Jena, Germany). The main outcome measures were uncorrected and best-corrected distance visual acuity, manifest refraction and corneal regularity by topographic images. The mean age was 34.75 ± 15.39 years and the follow-up time was 6 months for all patients.

Results: In three cases full subjective refraction was corrected in one session and one patient had a refractive error of +0.5 D. Only corneal surface smoothing without additional refractive correction was performed in this case. All four patients showed improvement in uncorrected (2-3 Snellen lines) and corrected (3 Snellen lines) distance visual acuity. No complications occurred during or after the treatment and there was no reduction of visual acuity in any case.

Conclusion: The use of TG-PRK in patients with corneal scarring improves visual acuity in selected cases. In myopic patients most of the refractive error can also be corrected in a single session.

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来源期刊
Ophthalmologe
Ophthalmologe 医学-眼科学
CiteScore
1.80
自引率
0.00%
发文量
95
审稿时长
4-8 weeks
期刊介绍: Der Ophthalmologe is an internationally recognized journal dealing with all aspects of ophthalmology. The journal serves both the scientific exchange and the continuing education of ophthalmologists. Freely submitted original papers allow the presentation of important clinical studies and serve scientific exchange. Case reports feature interesting cases and aim at optimizing diagnostic and therapeutic strategies. Comprehensive reviews on a specific topical issue focus on providing evidenced based information on diagnostics and therapy. Review articles under the rubric ''Continuing Medical Education'' present verified results of scientific research and their integration into daily practice.
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