p波离散度与肌钙蛋白联合预测阵发性心房颤动复发的临床价值

Metin Ocak , Mustafa Begenc Tascanov
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引用次数: 4

摘要

阵发性房颤(PAF)患者的p波离散度(PWD)和心肌肌钙蛋白水平与房颤(AF)复发独立相关。我们研究了联合PWD和心肌肌钙蛋白I预测急诊科PAF患者房颤复发的临床意义。方法本研究纳入65例PAF患者,根据基线肌钙蛋白I和PWD值分为3组(1组,肌钙蛋白I<0.11 ng/dl, PWD<44.5 ms;II组,肌钙蛋白I≥0.11 ng/dl, PWD≥44.5 ms,或肌钙蛋白I≥0.11 ng/dl, PWD≥44.5 ms;III组,肌钙蛋白I≥0.11 ng/dl, PWD≥44.5 ms)。结果ⅲ组AF复发率明显高于ⅰ组和ⅱ组。多因素分析显示,III组肌钙蛋白I和PWD值(优势比:7.236,95%可信区间:1.879 ~ 27.861,p=0.004)是房颤复发的独立预测因子。结论联合使用PWD和基础肌钙蛋白I水平比单独使用任何一种值更能预测房颤复发。
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Clinical value of the combined use of P-wave dispersion and troponin values to predict atrial fibrillation recurrence in patients with paroxysmal atrial fibrillation

Introduction

P-wave dispersion (PWD) and cardiac troponin levels are independently associated with the recurrence of atrial fibrillation (AF) in patients with paroxysmal AF (PAF). We investigated the clinical usefulness of combining PWD and cardiac troponin I to predict AF recurrence in patients presenting to the emergency department with PAF.

Methods

This study included 65 patients with PAF who were divided into three groups according to baseline troponin I and PWD values (group 1, troponin I<0.11 ng/dl and PWD<44.5 ms; group II, troponin I<0.11 ng/dl and PWD≥44.5 ms, or troponin I≥0.11 ng/dl and PWD<44.5 ms; group III, troponin I≥0.11 ng/dl and PWD≥44.5 ms).

Results

The AF recurrence rate was significantly higher in group III than in groups I and II. Multivariate analysis revealed that the troponin I and PWD values in group III (odds ratio: 7.236, 95% confidence interval: 1.879-27.861, p=0.004) were independent predictors of AF recurrence.

Conclusions

The combined use of PWD and basal troponin I levels is a better predictor of AF recurrence than either value alone.

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