干细胞是先天免疫系统和适应性免疫系统的一部分,可用于治疗Covid-19。

Q2 Agricultural and Biological Sciences Communicative and Integrative Biology Pub Date : 2021-09-10 eCollection Date: 2021-01-01 DOI:10.1080/19420889.2021.1965356
Greg Maguire
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引用次数: 6

摘要

一些干细胞类型不仅释放减少病毒复制的分子,还减少免疫系统诱导的高细胞动力学和炎症,并且被发现是先天和适应性免疫系统的一部分。干细胞改善病毒性疾病,特别是清除病原体后并发症的能力的一个重要组成部分是成年干细胞将先天和适应性免疫系统从炎症状态重置为修复状态的能力。因此,从某些类型的干细胞释放的分子被发现是安全有效的,可能是新冠肺炎治疗发展的重要新手段,尤其是在病毒清除后,尤其是老年人群中晚期炎症和组织损伤。
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Stem cells part of the innate and adaptive immune systems as a therapeutic for Covid-19.

Some stem cell types not only release molecules that reduce viral replication, but also reduce the hypercytokinemia and inflammation induced by the immune system, and have been found to be part of the innate and adaptive immune systems. An important component of the stem cell's ability to ameliorate viral diseases, especially the complications post-clearance of the pathogen, is the ability of adult stem cells to reset the innate and adaptive immune systems from an inflammatory state to a repair state. Thus, the molecules released from certain stem cell types found to be safe and efficacious, may be an important new means for therapeutic development in Covid-19, especially for late-stage inflammation and tissue damage once the virus has cleared, particularly in the aged population.

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来源期刊
Communicative and Integrative Biology
Communicative and Integrative Biology Agricultural and Biological Sciences-Agricultural and Biological Sciences (all)
CiteScore
3.50
自引率
0.00%
发文量
22
审稿时长
6 weeks
期刊最新文献
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