青春期端粒长度的人口统计学和发育模式。

IF 0.9 4区 社会学 Q3 DEMOGRAPHY Biodemography and Social Biology Pub Date : 2020-07-01 Epub Date: 2021-10-01 DOI:10.1080/19485565.2021.1983758
Lauren Gaydosh, Colter Mitchell, Daniel Notterman, Lisa Schneper, Jeanne Brooks-Gunn, Brandon Wagner, Kalsea Koss, Sara McLanahan
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引用次数: 0

摘要

端粒长度在成人研究中经常被用作细胞衰老的生物标志物和压力暴露的指标。然而,我们对端粒如何随时间变化知之甚少,尤其是在青春期的重要发育期。我们使用从脆弱家庭和儿童健康研究中收集的跨越青春期(9岁和15岁)的两个时间点的端粒长度数据来检查端粒长度的纵向模式(n=1654)。我们发现整个青春期的端粒长度在数量上很小但显著的平均延长,而且几乎没有证据表明端粒长度与青春期发育之间存在关联。
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Demographic and developmental patterns in telomere length across adolescence.

Telomere length is often used in studies of adults as a biomarker of cellular aging and an indicator of stress exposure. However, we know little about how telomeres change over time, particularly over the course of the important developmental period of adolescence. We use data on telomere length collected at two points in time spanning adolescence (Years 9 and 15) from the Fragile Families and Child Wellbeing Study to examine longitudinal patterns (n = 1,654) in telomere length. We find a quantitatively small but significant average lengthening in telomere length across adolescence and little evidence of associations between telomere length and pubertal development.

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来源期刊
CiteScore
1.50
自引率
0.00%
发文量
14
期刊介绍: Biodemography and Social Biology is the official journal of The Society for the Study of Social Biology, devoted to furthering the discussion, advancement, and dissemination of knowledge about biological and sociocultural forces affecting the structure and composition of human populations. This interdisciplinary publication features contributions from scholars in the fields of sociology, demography, psychology, anthropology, biology, genetics, criminal justice, and others. Original manuscripts that further knowledge in the area of social biology are welcome, along with brief reports, review articles, and book reviews.
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