宽带吸光度测量在识别成人艾滋病病毒感染者病理中耳方面的敏感性和特异性。

IF 1 Q3 AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY SOUTH AFRICAN JOURNAL OF COMMUNICATION DISORDERS Pub Date : 2021-09-30 DOI:10.4102/sajcd.v68i1.820
Ben Sebothoma, Katijah Khoza-Shangase, Duane Mol, Dipuo Masege
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引用次数: 0

摘要

背景:关于宽带声导抗(WAI)对成人艾滋病病毒感染者的敏感性和特异性的研究十分有限。本研究是题为 "成人艾滋病病毒感染者的宽带声阈值 "的大型研究的一部分:确定鼓室峰压(TPP)宽带吸声测量作为筛查工具检测成人 HIV 感染者中耳病变的敏感性和特异性:这项前瞻性非实验研究由 99 名成年艾滋病病毒感染者参加。所有参与者都接受了基本听力测试,包括病史、视频耳镜检查、鼓室测量、TPP 宽带吸声和纯音测听。两名耳鼻喉科医生通过异步视频耳镜图像分析确定中耳病变。耳鼻喉科医生的结果是衡量 TPP 宽带吸光度和鼓室测听的金标准。计算了接收器操作特性曲线(ROC):ROC显示,TPP的宽带吸光度对中低频的灵敏度较高,但对971.53赫兹以上频率的灵敏度明显较低。鼓室测量法的灵敏度较低。然而,TPP 的宽带吸光度与鼓室测压法的特异性没有差异,这表明在没有病变的情况下,鼓室测压法同样准确:目前的研究结果表明,TPP 的宽带吸光度比鼓室测压法更能区分中耳病变。将 TPP 宽带吸光度纳入临床实践可提高对中耳病变的早期识别和干预。
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The sensitivity and specificity of wideband absorbance measure in identifying pathologic middle ears in adults living with HIV.

Background: Limited research exists on the sensitivity and specificity of wideband acoustic immittance (WAI) in adults living with human immunodeficiency virus (HIV). This study forms part of the bigger study titled 'wideband acoustic immittance in adults living with HIV'.

Objectives: To determine the sensitivity and specificity of the wideband absorbance measure at tympanic peak pressure (TPP), as a screening tool for detecting middle ear pathologies in adults living with HIV.

Method: A prospective nonexperimental study comprising 99 adults living with HIV was performed. All participants underwent a basic audiological test battery which included case history, video otoscopy, tympanometry, wideband absorbance at TPP and pure tone audiometry. Middle ear pathologies were established by two otorhinolaryngologists using asynchronous video otoscopic images analysis. The outcomes of the otorhinolaryngologists served as the gold standard against which the wideband absorbance at TPP and tympanometry were measured. The receiver operating characteristics (ROC) curve was calculated.

Results: ROC revealed the sensitivity of wideband absorbance at TPP to be higher in low to mid frequencies, but significantly lower in frequencies above 971.53 Hz. The sensitivity of tympanometry was lower. However, there was no difference between the specificity of wideband absorbance at TPP and tympanometry, indicating that when there are no pathologies, tympanometry is equally accurate.

Conclusion: The current findings reveal that wideband absorbance at TPP can distinguish middle ear pathologies better than the tympanometry. Incorporating wideband absorbance at TPP in clinical practice may improve early identification and intervention of middle ear pathologies.

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来源期刊
SOUTH AFRICAN JOURNAL OF COMMUNICATION DISORDERS
SOUTH AFRICAN JOURNAL OF COMMUNICATION DISORDERS AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY-
CiteScore
2.10
自引率
36.40%
发文量
37
审稿时长
30 weeks
期刊最新文献
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