关于乳房植入物相关非典型大细胞淋巴瘤流行病学的新数据。

European journal of breast health Pub Date : 2021-10-04 eCollection Date: 2021-10-01 DOI:10.4274/ejbh.galenos.2021.2021-5-6
Paul Ionescu, Florence Vibert, Shanti Amé, Carole Mathelin
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引用次数: 0

摘要

研究目的本研究旨在通过关注2019年后发表的文章变化,尤其是乳房美容与整形手术的新方法,说明乳房植入物相关无性大细胞淋巴瘤(BIA-ALCL)的流行病学情况:使用PubMed数据库对2019年1月至今的文章进行了检索。14篇文章被纳入国际数据的定性评估中。此外,还确定了有关 BIA-ALCL 病例总数和死亡人数的最新报告:结果:据估计,该病的风险和发病率近来大幅上升,每2969名植入乳房假体的女性中就有1人患病,每355名乳房重建后植入纹理假体的患者中就有1人患病。从确诊到发病的平均接触时间为 8 年(范围:0-34 年)。约80%的BIA-ALC病例被诊断为IA-IIA期,其治疗方法是移除乳房假体、全帽切除术和切除所有可疑淋巴结。迄今为止,全球至少报告了 949 例病例:目前,BIA-ALCL 是一种新兴的病理学。自2016年起,通过不同的病例登记数据库开始收集数据,这对确保监测和继续增加对这一新发现病理的研究数量至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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New Data on the Epidemiology of Breast Implant-Associated Anaplastic Large Cell Lymphoma.

Objective: This study aimed to illustrate the epidemiological situation of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) by focusing on the changes published after 2019 and particularly the new approaches of cosmetic and reconstructive breast surgery.

Materials and methods: Article search was performed from January 2019 to date using the PubMed database. Fourteen articles were included in the qualitative evaluation of international data. Moreover, the latest reports regarding the total number of BIA-ALCL cases and number of deaths were identified.

Results: Estimates of the risk and incidence have increased significantly recently, affecting 1 in every 2,969 women with breast implants and 1 in 355 patients with textured implants after breast reconstruction. The average exposure time to diagnosis was 8 (range: 0-34) years. Approximately 80% of BIA-ALCL cases were diagnosed at IA-IIA stages, for which the treatment was breast implant removal, full capsulectomy, and excision of all suspected lymph nodes. Globally, at least 949 cases were reported to date.

Conclusion: At present, BIA-ALCL is an emerging pathology of interest. Data collection initiated since 2016 through different case registration databases is essential to ensure surveillance and to continue to increase the number of studies on this recently discovered pathology.

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