土族塞人冠心病患者的危险因素。

Cenk Conkbayir, Didem Melis Oztas, Murat Ugurlucan
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摘要

缺血性心脏病是世界范围内死亡的主要原因。在这项研究中,我们评估了土族塞人缺血性心脏病患者的危险因素。材料和方法:在本研究中,我们回顾性检查了7017例患者。5.9%的患者发生心肌梗死冠状动脉疾病(MICAD), 94.1%的患者为对照组。研究人群的平均年龄为52岁,其中39.2%为女性。考虑的危险因素有:年龄、性别、高血压(HT)、糖尿病(DM)、冠状动脉疾病家族史、吸烟、高总胆固醇水平和肥胖。结果:与假定的危险因素一致,在我们的研究中,MICAD与对照组在吸烟、HT、DM和肥胖方面存在显著差异。然而,我们的研究显示,与目前的文献相比,高总胆固醇水平没有显著差异。在分别评估男性和女性患者组的危险因素时,男性和女性的高血压患病率最高。吸烟是男性中第二常见的危险因素,而女性中最常见的危险因素是冠心病家族史。在我们的研究组中,HT、DM和肥胖是男性和女性的重要危险因素,而家族史仅在女性中具有重要意义。结论:吸烟、高血压、糖尿病、肥胖等可改变的危险因素可通过改变生活方式和药物治疗加以控制,应谨慎处理,预防发生心脏事件。不可改变的风险因素,如年龄、性别、家族史和种族,应考虑到疾病预测。
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Risk factors for Turkish Cypriot patients with coronary artery disease.

Introduction: Ischemic heart disease is the leading cause of death worldwide. In this study, we evaluated the risk factors for Turkish Cypriot ischemic heart disease patients.

Material and methods: In this study we examined 7017 patients, retrospectively. 5.9% of the patients had myocardial infarction coronary artery disease (MICAD) and 94.1% of the patients were control patients. The mean age of the study population was 52, and 39.2% were female. The risk factors considered were: age, sex, hypertension (HT), diabetes mellitus (DM), family history of coronary artery disease, smoking, high total cholesterol levels and obesity.

Results: Consistently with the presumed risk factors, there was a significant difference between MICAD and control groups in our study for smoking, HT, DM and obesity. However, our study revealed no significant difference for high total cholesterol levels in contrast to the current literature. Assessing the risk factors among male and female patient groups separately, both men and women have the highest risk prevalence for hypertension. Smoking is the second most common risk factor among males, whereas it is the family history of coronary heart disease in the female group. HT, DM and obesity were found to be significant risk factors for both males and females in our study group, while family history was revealed to be significant only in women.

Conclusions: Modifiable risk factors such as smoking, hypertension, diabetes mellitus and obesity may be controlled by lifestyle changes and medical therapies, and should be approached with caution for preventing cardiac events. Non-modifiable risk factors such as age, gender, family history and ethnicity should be taken into account for disease prediction.

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