肾去神经支配:真的是降低血压的替代方法吗?]

4区 医学 Q3 Medicine Internist Pub Date : 2022-03-01 Epub Date: 2022-01-14 DOI:10.1007/s00108-021-01242-3
Kristina Striepe, Mario Schiffer, Roland Schmieder
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引用次数: 0

摘要

自现行指南于2018年发布以来,共进行了5项评估肾去神经的假对照高质量研究,并发表了结果。这五项研究明确证实了肾去神经支配的有效性和安全性,与临床共识会议的认识相对应。因此,关于肾去神经支配的临床意义的动脉性高血压治疗指南的更新是迫切需要的。为此,对欧洲高血压学会工作组关于肾去神经支配现状的立场文件进行了综述。这一程序有望很快获得批准。在德国,有一个诊断相关组(DRG)用于肾去神经治疗的报销,由于错误的Symplicity 3研究而暂停。这种DRG应该在实践中通过实施肾去神经的结构化过程来恢复。然后,在认证中心的治疗医生和专家将共同完成一项任务,以确定合格的患者。在未来,降压治疗将包括三个支柱:生活方式措施、药物治疗和介入治疗。这三种治疗方案不应被视为竞争(哪个更好),而应被视为替代(患者偏好)和附加(目的是控制血压)。为患者提供理想的治疗理念是治疗医师的任务。显然,肾去神经不能取代降压药物治疗;然而,它可以减少药物负担并增加患者对药物的依从性。它代表了现代抗高血压治疗的一种选择,在特殊患者群体中也将变得越来越重要。
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[Renal denervation : Really an alternative to reducing blood pressure?]

Since the current guidelines were published in 2018, a total of 5 sham-controlled high-quality studies evaluating renal denervation have been conducted and the results were published. These five studies clearly confirmed the efficacy and safety of renal denervation, which correspond to the knowledge of the Clinical Consensus Conference. Thus, an update of the guidelines for the treatment of arterial hypertension regarding the clinical significance of renal denervation is urgently necessary. For this reason, the position paper of the working group of the European Society of Hypertension on the current state of renal denervation was reviewed. An approval of this procedure can soon be expected. In Germany there is a diagnosis-related group (DRG) for the reimbursement of renal denervation, which was suspended due to the erroneous Symplicity 3 study. This DRG should be revived in practice by a structured process of the implementation of renal denervation. It will then be a joint task of treating physicians and specialists in certified centers to identify eligible patients. In the future, antihypertensive treatment will consist of three pillars: lifestyle measures, pharmacotherapy and interventional treatment. These three treatment options should not be regarded as competitive (which is better) but alternative (patient preference) and additive (the aim is blood pressure control). It is the task of the treating physician to provide the patient with the ideal treatment concept. Clearly, renal denervation will not replace antihypertensive pharmacotherapy; however, it can lead to a reduction of the drug burden and increase of patient adherence to medication. It represents an option of modern antihypertensive treatment and will also become increasingly more important in special patient groups.

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来源期刊
Internist
Internist 医学-医学:内科
CiteScore
1.20
自引率
0.00%
发文量
139
审稿时长
4-8 weeks
期刊介绍: Der Internist is an internationally respected journal dealing with all aspects of internal medicine. The journal serves both the scientific exchange and the continuing education of internists working in practical or clinical environments as well as of general practitioners who are particularly interested in internal medicine. The focus is on the topics of prevention, diagnostic approaches, management of complications, and current therapy strategies. Comprehensive reviews on a specific topical issue focus on providing evidenced based information on diagnostics and therapy. Case reports feature interesting cases and aim at optimizing diagnostic and therapeutic strategies. Review articles under the rubric "Continuing Medical Education" present verified results of scientific research and their integration into daily practice.
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