复发性成人骶尾畸胎瘤发展为腺癌1例报告及文献复习。

IF 0.7 Q4 PATHOLOGY Case Reports in Pathology Pub Date : 2021-11-27 eCollection Date: 2021-01-01 DOI:10.1155/2021/5045250
Shengjie Cui, Jing Han, Binny Khandakar, Barak Friedman, Domingo Nunez, Gabriel A Sara, Gabriel S Levi
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引用次数: 1

摘要

骶尾翼畸胎瘤(SCT)最常见于婴儿和儿童,但在成人中很少见。大多数成人SCT是良性和成熟的,少数肿瘤具有不成熟的成分或明显的恶性肿瘤。在此,我们报告一位65岁女性SCT发展为腺癌。患者在首次就诊时被诊断为良性骶尾骨囊性畸胎瘤,并接受手术切除治疗。术后随访,术后13个月CA 19-9水平明显升高。放射学和临床检查显示直肠周围软组织增厚,位于先前切口的下部附近。组织学检查显示为浸润性中分化腺癌。免疫组化染色结果提示,但不能诊断为肛门腺腺癌。本病例报告扩展了对先前良性成人SCT引起的腺癌的认识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Recurrent Adult Sacrococcygeal Teratoma Developing Adenocarcinoma: A Case Report and Review of Literatures.

Sacrococcygeal teratomas (SCT) are most commonly seen in infants and children but are rare in adults. Most adult SCT are benign and mature with a minority of tumors having immature components or overt malignancy. Here, we report a 65-year-old female with a SCT developing adenocarcinoma. The patient was diagnosed with benign sacrococcygeal cystic teratoma on her initial hospital visit and was treated with surgical resection. She was followed up postoperatively and was noted to have a markedly elevated CA 19-9 level 13 months after the surgery. Radiological and clinical examination revealed thickening of the perirectal soft tissues, located near the inferior portion of her previous incision site. Histological evaluation of the lesion showed invasive, moderately differentiated adenocarcinoma. Immunohistochemical staining results were suggestive, but not diagnostic, of anal gland adenocarcinoma. This case report expands the knowledge regarding an adenocarcinoma arising from a previously benign, adult SCT.

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