R. Mustafaoglu , A. Gorek Dilektaslı , R. Demir , E. Zirek , T. Birinci , E. Kaya Mutlu , C. Evren , A. Razak Ozdincler
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The III National Health and Nutrition Examination Survey were used to evaluate respiratory symptoms in patients with SUD and cigarette smokers.</p></div><div><h3>Results</h3><p>86.3% of the SUD patients included in the study were using heroin, 9.2% were cannabis, and 5.5% were spice. The most common symptom in both SUD patients and cigarette smokers was shortness of breath, wheezing, and sputum production. After post-hoc tests, the FVC (<em>p</em> = 0.002), FVC (%predicted) (<em>p</em> < 0.0001), FEV<sub>1</sub> (<em>p =</em> 0.002), FEV1 (%predicted) (<em>p <</em> 0.0001), FEV<sub>1</sub>/FVC (%) (<em>p <</em> 0.0001), PEF (<em>p <</em> 0.0001) and FEF<sub>%25-75</sub> (<em>p <</em> 0.0001) lung function parameters were significantly lower in SUD patients than non-smokers. In addition, it was found that MIP (<em>p <</em> 0.0001), MIP (%predicted) (<em>p <</em> 0.0001), MEP (<em>p <</em> 0.0001), and MEP (%predicted) (<em>p <</em> 0.0001) values of SUD patients were significantly lower than non-smokers.</p></div><div><h3>Conclusion</h3><p>The study findings indicate that substance use has an effect on lung functions and the most commonly reported symptoms are shortness of breath, wheezing, and sputum production. In addition, respiratory muscle strength and exercise capacity were decreased in SUD patients compared to non-smokers.</p></div>","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"30 3","pages":"Pages 254-264"},"PeriodicalIF":10.4000,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S253104372200006X/pdfft?md5=4a187dbf14500f064e3cbd9cc3870cf6&pid=1-s2.0-S253104372200006X-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Exercise capacity, lung and respiratory muscle function in substance use disorders\",\"authors\":\"R. Mustafaoglu , A. Gorek Dilektaslı , R. Demir , E. Zirek , T. Birinci , E. Kaya Mutlu , C. Evren , A. 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引用次数: 0
摘要
背景:物质使用障碍(SUD)会导致认知和行为障碍、焦虑、抑郁和社会隔离等症状,还会通过影响气道支气管动力学而引起急性气道炎症。本研究旨在调查 SUD 患者的肺功能、呼吸肌强度和运动能力:研究纳入了 183 名 SUD 患者和 119 名健康对照者,其中 54 人为吸烟者,65 人为非吸烟者。研究人员对肺活量测试、呼吸肌力量(MIP 和 MEP)以及 6 分钟步行测试(6-MWT)进行了评估。第三次全国健康与营养调查用于评估 SUD 患者和吸烟者的呼吸道症状:86.3%的 SUD 患者吸食海洛因,9.2%吸食大麻,5.5%吸食香料。吸毒成瘾患者和吸烟者最常见的症状都是气短、喘息和痰多。经过事后检验,FVC (p = 0.002)、FVC (%predicted) (p 1 (p = 0.002)、FEV1 (%predicted) (p 1/FVC (%) (p %25-75 (p 结论:研究结果表明,药物使用对肺功能有影响,最常报告的症状是气短、喘息和痰多。此外,与非吸烟者相比,吸食成瘾患者的呼吸肌强度和运动能力均有所下降。
Exercise capacity, lung and respiratory muscle function in substance use disorders
Background
Substance use disorder (SUD) causes conditions such as cognitive and behavioral disorders, anxiety, depression, and social isolation it also causes acute airway inflammation by affecting airway bronchial dynamics. The current study aimed to investigate the lung function, respiratory muscle strength, and exercise capacity in patients with SUD.
Methods
One hundred-eighty three patients with SUD, a total of 119 healthy controls, 54 of whom were cigarette smokers and 65 of whom were non-smokers were included in the study. Spirometric tests, respiratory muscle strength (MIP and MEP), and the 6-Minute Walk Test (6-MWT) were assessed. The III National Health and Nutrition Examination Survey were used to evaluate respiratory symptoms in patients with SUD and cigarette smokers.
Results
86.3% of the SUD patients included in the study were using heroin, 9.2% were cannabis, and 5.5% were spice. The most common symptom in both SUD patients and cigarette smokers was shortness of breath, wheezing, and sputum production. After post-hoc tests, the FVC (p = 0.002), FVC (%predicted) (p < 0.0001), FEV1 (p = 0.002), FEV1 (%predicted) (p < 0.0001), FEV1/FVC (%) (p < 0.0001), PEF (p < 0.0001) and FEF%25-75 (p < 0.0001) lung function parameters were significantly lower in SUD patients than non-smokers. In addition, it was found that MIP (p < 0.0001), MIP (%predicted) (p < 0.0001), MEP (p < 0.0001), and MEP (%predicted) (p < 0.0001) values of SUD patients were significantly lower than non-smokers.
Conclusion
The study findings indicate that substance use has an effect on lung functions and the most commonly reported symptoms are shortness of breath, wheezing, and sputum production. In addition, respiratory muscle strength and exercise capacity were decreased in SUD patients compared to non-smokers.
PulmonologyMedicine-Pulmonary and Respiratory Medicine
CiteScore
14.30
自引率
5.10%
发文量
159
审稿时长
19 days
期刊介绍:
Pulmonology (previously Revista Portuguesa de Pneumologia) is the official journal of the Portuguese Society of Pulmonology (Sociedade Portuguesa de Pneumologia/SPP). The journal publishes 6 issues per year and focuses on respiratory system diseases in adults and clinical research. It accepts various types of articles including peer-reviewed original articles, review articles, editorials, and opinion articles. The journal is published in English and is freely accessible through its website, as well as Medline and other databases. It is indexed in Science Citation Index Expanded, Journal of Citation Reports, Index Medicus/MEDLINE, Scopus, and EMBASE/Excerpta Medica.