药物使用失调症患者的运动能力、肺功能和呼吸肌功能。

IF 10.4 2区 医学 Q1 RESPIRATORY SYSTEM Pulmonology Pub Date : 2024-05-01 DOI:10.1016/j.pulmoe.2021.12.009
R. Mustafaoglu , A. Gorek Dilektaslı , R. Demir , E. Zirek , T. Birinci , E. Kaya Mutlu , C. Evren , A. Razak Ozdincler
{"title":"药物使用失调症患者的运动能力、肺功能和呼吸肌功能。","authors":"R. Mustafaoglu ,&nbsp;A. Gorek Dilektaslı ,&nbsp;R. Demir ,&nbsp;E. Zirek ,&nbsp;T. Birinci ,&nbsp;E. Kaya Mutlu ,&nbsp;C. Evren ,&nbsp;A. Razak Ozdincler","doi":"10.1016/j.pulmoe.2021.12.009","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Substance use disorder (SUD) causes conditions such as cognitive and behavioral disorders, anxiety, depression, and social isolation it also causes acute airway inflammation by affecting airway bronchial dynamics. The current study aimed to investigate the lung function, respiratory muscle strength, and exercise capacity in patients with SUD.</p></div><div><h3>Methods</h3><p>One hundred-eighty three patients with SUD, a total of 119 healthy controls, 54 of whom were cigarette smokers and 65 of whom were non-smokers were included in the study. <strong>S</strong>pirometric tests, respiratory muscle strength (MIP and MEP), and the 6-Minute Walk Test (6-MWT) were assessed. The III National Health and Nutrition Examination Survey were used to evaluate respiratory symptoms in patients with SUD and cigarette smokers.</p></div><div><h3>Results</h3><p>86.3% of the SUD patients included in the study were using heroin, 9.2% were cannabis, and 5.5% were spice. The most common symptom in both SUD patients and cigarette smokers was shortness of breath, wheezing, and sputum production. After post-hoc tests, the FVC (<em>p</em> = 0.002), FVC (%predicted) (<em>p</em> &lt; 0.0001), FEV<sub>1</sub> (<em>p =</em> 0.002), FEV1 (%predicted) (<em>p &lt;</em> 0.0001), FEV<sub>1</sub>/FVC (%) (<em>p &lt;</em> 0.0001), PEF (<em>p &lt;</em> 0.0001) and FEF<sub>%25-75</sub> (<em>p &lt;</em> 0.0001) lung function parameters were significantly lower in SUD patients than non-smokers. In addition, it was found that MIP (<em>p &lt;</em> 0.0001), MIP (%predicted) (<em>p &lt;</em> 0.0001), MEP (<em>p &lt;</em> 0.0001), and MEP (%predicted) (<em>p &lt;</em> 0.0001) values of SUD patients were significantly lower than non-smokers.</p></div><div><h3>Conclusion</h3><p>The study findings indicate that substance use has an effect on lung functions and the most commonly reported symptoms are shortness of breath, wheezing, and sputum production. In addition, respiratory muscle strength and exercise capacity were decreased in SUD patients compared to non-smokers.</p></div>","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":null,"pages":null},"PeriodicalIF":10.4000,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S253104372200006X/pdfft?md5=4a187dbf14500f064e3cbd9cc3870cf6&pid=1-s2.0-S253104372200006X-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Exercise capacity, lung and respiratory muscle function in substance use disorders\",\"authors\":\"R. Mustafaoglu ,&nbsp;A. Gorek Dilektaslı ,&nbsp;R. Demir ,&nbsp;E. Zirek ,&nbsp;T. Birinci ,&nbsp;E. Kaya Mutlu ,&nbsp;C. Evren ,&nbsp;A. Razak Ozdincler\",\"doi\":\"10.1016/j.pulmoe.2021.12.009\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>Substance use disorder (SUD) causes conditions such as cognitive and behavioral disorders, anxiety, depression, and social isolation it also causes acute airway inflammation by affecting airway bronchial dynamics. The current study aimed to investigate the lung function, respiratory muscle strength, and exercise capacity in patients with SUD.</p></div><div><h3>Methods</h3><p>One hundred-eighty three patients with SUD, a total of 119 healthy controls, 54 of whom were cigarette smokers and 65 of whom were non-smokers were included in the study. <strong>S</strong>pirometric tests, respiratory muscle strength (MIP and MEP), and the 6-Minute Walk Test (6-MWT) were assessed. The III National Health and Nutrition Examination Survey were used to evaluate respiratory symptoms in patients with SUD and cigarette smokers.</p></div><div><h3>Results</h3><p>86.3% of the SUD patients included in the study were using heroin, 9.2% were cannabis, and 5.5% were spice. The most common symptom in both SUD patients and cigarette smokers was shortness of breath, wheezing, and sputum production. After post-hoc tests, the FVC (<em>p</em> = 0.002), FVC (%predicted) (<em>p</em> &lt; 0.0001), FEV<sub>1</sub> (<em>p =</em> 0.002), FEV1 (%predicted) (<em>p &lt;</em> 0.0001), FEV<sub>1</sub>/FVC (%) (<em>p &lt;</em> 0.0001), PEF (<em>p &lt;</em> 0.0001) and FEF<sub>%25-75</sub> (<em>p &lt;</em> 0.0001) lung function parameters were significantly lower in SUD patients than non-smokers. In addition, it was found that MIP (<em>p &lt;</em> 0.0001), MIP (%predicted) (<em>p &lt;</em> 0.0001), MEP (<em>p &lt;</em> 0.0001), and MEP (%predicted) (<em>p &lt;</em> 0.0001) values of SUD patients were significantly lower than non-smokers.</p></div><div><h3>Conclusion</h3><p>The study findings indicate that substance use has an effect on lung functions and the most commonly reported symptoms are shortness of breath, wheezing, and sputum production. In addition, respiratory muscle strength and exercise capacity were decreased in SUD patients compared to non-smokers.</p></div>\",\"PeriodicalId\":54237,\"journal\":{\"name\":\"Pulmonology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":10.4000,\"publicationDate\":\"2024-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S253104372200006X/pdfft?md5=4a187dbf14500f064e3cbd9cc3870cf6&pid=1-s2.0-S253104372200006X-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pulmonology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S253104372200006X\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"RESPIRATORY SYSTEM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pulmonology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S253104372200006X","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"RESPIRATORY SYSTEM","Score":null,"Total":0}
引用次数: 0

摘要

背景:物质使用障碍(SUD)会导致认知和行为障碍、焦虑、抑郁和社会隔离等症状,还会通过影响气道支气管动力学而引起急性气道炎症。本研究旨在调查 SUD 患者的肺功能、呼吸肌强度和运动能力:研究纳入了 183 名 SUD 患者和 119 名健康对照者,其中 54 人为吸烟者,65 人为非吸烟者。研究人员对肺活量测试、呼吸肌力量(MIP 和 MEP)以及 6 分钟步行测试(6-MWT)进行了评估。第三次全国健康与营养调查用于评估 SUD 患者和吸烟者的呼吸道症状:86.3%的 SUD 患者吸食海洛因,9.2%吸食大麻,5.5%吸食香料。吸毒成瘾患者和吸烟者最常见的症状都是气短、喘息和痰多。经过事后检验,FVC (p = 0.002)、FVC (%predicted) (p 1 (p = 0.002)、FEV1 (%predicted) (p 1/FVC (%) (p %25-75 (p 结论:研究结果表明,药物使用对肺功能有影响,最常报告的症状是气短、喘息和痰多。此外,与非吸烟者相比,吸食成瘾患者的呼吸肌强度和运动能力均有所下降。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Exercise capacity, lung and respiratory muscle function in substance use disorders

Background

Substance use disorder (SUD) causes conditions such as cognitive and behavioral disorders, anxiety, depression, and social isolation it also causes acute airway inflammation by affecting airway bronchial dynamics. The current study aimed to investigate the lung function, respiratory muscle strength, and exercise capacity in patients with SUD.

Methods

One hundred-eighty three patients with SUD, a total of 119 healthy controls, 54 of whom were cigarette smokers and 65 of whom were non-smokers were included in the study. Spirometric tests, respiratory muscle strength (MIP and MEP), and the 6-Minute Walk Test (6-MWT) were assessed. The III National Health and Nutrition Examination Survey were used to evaluate respiratory symptoms in patients with SUD and cigarette smokers.

Results

86.3% of the SUD patients included in the study were using heroin, 9.2% were cannabis, and 5.5% were spice. The most common symptom in both SUD patients and cigarette smokers was shortness of breath, wheezing, and sputum production. After post-hoc tests, the FVC (p = 0.002), FVC (%predicted) (p < 0.0001), FEV1 (p = 0.002), FEV1 (%predicted) (p < 0.0001), FEV1/FVC (%) (p < 0.0001), PEF (p < 0.0001) and FEF%25-75 (p < 0.0001) lung function parameters were significantly lower in SUD patients than non-smokers. In addition, it was found that MIP (p < 0.0001), MIP (%predicted) (p < 0.0001), MEP (p < 0.0001), and MEP (%predicted) (p < 0.0001) values of SUD patients were significantly lower than non-smokers.

Conclusion

The study findings indicate that substance use has an effect on lung functions and the most commonly reported symptoms are shortness of breath, wheezing, and sputum production. In addition, respiratory muscle strength and exercise capacity were decreased in SUD patients compared to non-smokers.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Pulmonology
Pulmonology Medicine-Pulmonary and Respiratory Medicine
CiteScore
14.30
自引率
5.10%
发文量
159
审稿时长
19 days
期刊介绍: Pulmonology (previously Revista Portuguesa de Pneumologia) is the official journal of the Portuguese Society of Pulmonology (Sociedade Portuguesa de Pneumologia/SPP). The journal publishes 6 issues per year and focuses on respiratory system diseases in adults and clinical research. It accepts various types of articles including peer-reviewed original articles, review articles, editorials, and opinion articles. The journal is published in English and is freely accessible through its website, as well as Medline and other databases. It is indexed in Science Citation Index Expanded, Journal of Citation Reports, Index Medicus/MEDLINE, Scopus, and EMBASE/Excerpta Medica.
期刊最新文献
Prone position for acute respiratory distress syndrome and the hazards of meta-analysis Associations and relative risks of pulmonary hypertension and lung diseases in individuals with methamphetamine use disorder Issue 2 - “Update on adverse respiratory effects of indoor air pollution”. Part 2): Indoor air pollution and respiratory diseases: Perspectives from Italy and some other GARD countries Profile of emergency department overuse in hospitalized patients with pulmonary disease and its impact on mortality Single breath nitrogen test as predictor of lung function decline and COPD over an 8-year follow-up
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1