Vincenzo Damico, Alberto Dal Molin, Liana Murano, Viola Margosio, Erica Busca, Clara Ripamonti
{"title":"[COVID-19爆发期间的医院感染]。意大利ICU的观察性研究]。","authors":"Vincenzo Damico, Alberto Dal Molin, Liana Murano, Viola Margosio, Erica Busca, Clara Ripamonti","doi":"10.1702/3743.37259","DOIUrl":null,"url":null,"abstract":"<p><p>. Nosocomial infections during the COVID-19 outbreak. Observational study in an Italian ICU.</p><p><strong>Introduction: </strong>Infections are common among ICU patients.</p><p><strong>Aim: </strong>The purpose of this study is to examine the incidence of nosocomial infections among patients admitted to the ICU with SARS-CoV-2 infection.</p><p><strong>Methods: </strong>A prospective observational study in adults with confirmed SARS-CoV-2 infection requiring intensive care unit (ICU) admission was performed. From May 2020 to October 2021, a total of 109 admitted patients were included.</p><p><strong>Results: </strong>The incidence rate of new infections was 39.4%. The main infections observed were multidrug-resistant germs infections (39.5%), catheter-related blood infections(24.4%), pneumonia (VAP)(18.6%), and urinary tract infections (17.4%). The overall mortality rate was 32.1% (n= 35) and was significantly higher in patients who had a new infection during hospitalization (n= 26/43, 60.4%) than in patients who did not have a new infection (n= 9/66, 13.6%) (RR = 4.43; 95% CI = 2.31-8.52; p <.001).</p><p><strong>Conclusions: </strong>Our data suggest that secondary infections are associated with a longer duration of mechanical ventilation and hospital stay and may negatively impact patient survival. However, larger studies are needed.</p>","PeriodicalId":55447,"journal":{"name":"Assistenza Infermieristica E Ricerca","volume":"40 4","pages":"205-212"},"PeriodicalIF":0.8000,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"[Nosocomial infections during the COVID-19 outbreak. Observational study in an Italian ICU].\",\"authors\":\"Vincenzo Damico, Alberto Dal Molin, Liana Murano, Viola Margosio, Erica Busca, Clara Ripamonti\",\"doi\":\"10.1702/3743.37259\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>. Nosocomial infections during the COVID-19 outbreak. Observational study in an Italian ICU.</p><p><strong>Introduction: </strong>Infections are common among ICU patients.</p><p><strong>Aim: </strong>The purpose of this study is to examine the incidence of nosocomial infections among patients admitted to the ICU with SARS-CoV-2 infection.</p><p><strong>Methods: </strong>A prospective observational study in adults with confirmed SARS-CoV-2 infection requiring intensive care unit (ICU) admission was performed. From May 2020 to October 2021, a total of 109 admitted patients were included.</p><p><strong>Results: </strong>The incidence rate of new infections was 39.4%. The main infections observed were multidrug-resistant germs infections (39.5%), catheter-related blood infections(24.4%), pneumonia (VAP)(18.6%), and urinary tract infections (17.4%). The overall mortality rate was 32.1% (n= 35) and was significantly higher in patients who had a new infection during hospitalization (n= 26/43, 60.4%) than in patients who did not have a new infection (n= 9/66, 13.6%) (RR = 4.43; 95% CI = 2.31-8.52; p <.001).</p><p><strong>Conclusions: </strong>Our data suggest that secondary infections are associated with a longer duration of mechanical ventilation and hospital stay and may negatively impact patient survival. However, larger studies are needed.</p>\",\"PeriodicalId\":55447,\"journal\":{\"name\":\"Assistenza Infermieristica E Ricerca\",\"volume\":\"40 4\",\"pages\":\"205-212\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2021-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Assistenza Infermieristica E Ricerca\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1702/3743.37259\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"NURSING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Assistenza Infermieristica E Ricerca","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1702/3743.37259","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"NURSING","Score":null,"Total":0}
[Nosocomial infections during the COVID-19 outbreak. Observational study in an Italian ICU].
. Nosocomial infections during the COVID-19 outbreak. Observational study in an Italian ICU.
Introduction: Infections are common among ICU patients.
Aim: The purpose of this study is to examine the incidence of nosocomial infections among patients admitted to the ICU with SARS-CoV-2 infection.
Methods: A prospective observational study in adults with confirmed SARS-CoV-2 infection requiring intensive care unit (ICU) admission was performed. From May 2020 to October 2021, a total of 109 admitted patients were included.
Results: The incidence rate of new infections was 39.4%. The main infections observed were multidrug-resistant germs infections (39.5%), catheter-related blood infections(24.4%), pneumonia (VAP)(18.6%), and urinary tract infections (17.4%). The overall mortality rate was 32.1% (n= 35) and was significantly higher in patients who had a new infection during hospitalization (n= 26/43, 60.4%) than in patients who did not have a new infection (n= 9/66, 13.6%) (RR = 4.43; 95% CI = 2.31-8.52; p <.001).
Conclusions: Our data suggest that secondary infections are associated with a longer duration of mechanical ventilation and hospital stay and may negatively impact patient survival. However, larger studies are needed.
期刊介绍:
Assistenza Infermieristica e Ricerca (AIR) è una rivista scientifica che si propone l''obiettivo di promuovere e sviluppare il confronto sulle conoscenze che hanno un impatto sulla pratica, sulla formazione e sulla direzione dell''assistenza infermieristica.