[COVID-19爆发期间的医院感染]。意大利ICU的观察性研究]。

IF 0.8 4区 医学 Q4 NURSING Assistenza Infermieristica E Ricerca Pub Date : 2021-10-01 DOI:10.1702/3743.37259
Vincenzo Damico, Alberto Dal Molin, Liana Murano, Viola Margosio, Erica Busca, Clara Ripamonti
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引用次数: 1

摘要

. COVID-19疫情期间的医院感染。意大利ICU的观察性研究。感染在ICU患者中很常见。目的:探讨重症监护病房收治的SARS-CoV-2感染患者的院内感染发生率。方法:对确诊为SARS-CoV-2感染、需要入住重症监护病房(ICU)的成人进行前瞻性观察研究。从2020年5月至2021年10月,共纳入109例住院患者。结果:新发感染率为39.4%。主要感染为耐多药菌感染(39.5%)、导管相关血液感染(24.4%)、肺炎(18.6%)和尿路感染(17.4%)。总死亡率为32.1% (n= 35),住院期间发生新感染的患者(n= 26/43, 60.4%)的总死亡率显著高于未发生新感染的患者(n= 9/66, 13.6%) (RR = 4.43;95% ci = 2.31-8.52;结论:我们的数据表明继发感染与较长的机械通气时间和住院时间相关,并可能对患者的生存产生负面影响。然而,还需要更大规模的研究。
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[Nosocomial infections during the COVID-19 outbreak. Observational study in an Italian ICU].

. Nosocomial infections during the COVID-19 outbreak. Observational study in an Italian ICU.

Introduction: Infections are common among ICU patients.

Aim: The purpose of this study is to examine the incidence of nosocomial infections among patients admitted to the ICU with SARS-CoV-2 infection.

Methods: A prospective observational study in adults with confirmed SARS-CoV-2 infection requiring intensive care unit (ICU) admission was performed. From May 2020 to October 2021, a total of 109 admitted patients were included.

Results: The incidence rate of new infections was 39.4%. The main infections observed were multidrug-resistant germs infections (39.5%), catheter-related blood infections(24.4%), pneumonia (VAP)(18.6%), and urinary tract infections (17.4%). The overall mortality rate was 32.1% (n= 35) and was significantly higher in patients who had a new infection during hospitalization (n= 26/43, 60.4%) than in patients who did not have a new infection (n= 9/66, 13.6%) (RR = 4.43; 95% CI = 2.31-8.52; p <.001).

Conclusions: Our data suggest that secondary infections are associated with a longer duration of mechanical ventilation and hospital stay and may negatively impact patient survival. However, larger studies are needed.

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来源期刊
CiteScore
1.30
自引率
18.20%
发文量
24
审稿时长
>12 weeks
期刊介绍: Assistenza Infermieristica e Ricerca (AIR) è una rivista scientifica che si propone l''obiettivo di promuovere e sviluppare il confronto sulle conoscenze che hanno un impatto sulla pratica, sulla formazione e sulla direzione dell''assistenza infermieristica.
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