Kathleen V Fitch, Meghan Noonan Feldpausch, Sara E Dolan Looby
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Biomarkers and Clinical Indices of Aging with HIV.
HIV infection may potentiate specific biomarkers that influence the development of premature clinical indices commonly associated with aging. Therefore, predicting mortality outcomes in people living with HIV is extremely important as this population ages. This chapter describes biomarkers associated with inflammation, coagulation, and immune activation in HIV, and reviews the association between specific biomarkers and the development of co-morbid conditions in individuals with HIV. Measures that incorporate specific biomarkers related to HIV infection, designed to predict mortality outcomes in individuals with HIV, are also discussed.
期刊介绍:
At a time when interest in the process of aging is driving more and more research, ''Interdisciplinary Topics in Gerontology and Geriatrics'' offers investigators a way to stay at the forefront of developments. This series represents a comprehensive and integrated approach to the problems of aging and presents pertinent data from studies in animal and human gerontology. In order to provide a forum for a unified concept of gerontology, both the biological foundations and the clinical and sociological consequences of aging in humans are presented. Individual volumes are characterized by an analytic overall view of the aging process, novel ideas, and original approaches to healthy aging as well as age-related functional decline.