患者特定心血管系统模拟中血液流变学模型的比较

IF 3.4 3区 工程技术 Q1 MECHANICS 水动力学研究与进展:英文版 Pub Date : 2017-04-01 DOI:10.1016/S1001-6058(16)60739-4
Anastasios Skiadopoulos, Panagiotis Neofytou, Christos Housiadas
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引用次数: 28

摘要

牛顿,Quemada和Casson血液粘度模型的实施,以模拟搏动血流条件下的血液流变学行为在患者特定的髂分叉。根据剪切速率,通过壁面剪切应力(WSS)分布、大小和振荡、非牛顿重要因子和粘度值来监测应用的血液本质方程的影响。WSS在血管壁上的分布遵循一种与所选择的流变模型无关的模式。另一方面,WSS的大小和振荡与应用的血液本构方程和剪切速率直接相关。结论是,牛顿近似只有在高剪切速率和高流速下才令人满意。此外,牛顿模型似乎高估了在WSS振荡的血管壁部位形成动脉粥样硬化病变或动脉瘤的可能性。
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Comparison of blood rheological models in patient specific cardiovascular system simulations

Newtonian, Quemada and Casson blood viscosity models are implemented in order to simulate the rheological behavior of blood under pulsating flow conditions in a patient specific iliac bifurcation. The influence of the applied blood constitutive equations is monitored via the wall shear stress (WSS) distribution, magnitude and oscillations, non-Newtonian importance factors, and viscosity values according to the shear rate. The distribution of WSS on the vascular wall follows a pattern which is independent of the rheological model chosen. On the other hand, the WSS magnitude and oscillations are directly related to the blood constitutive equations applied and the shear rate. It is concluded that the Newtonian approximation is satisfactory only in high shear and flow rates. Moreover, the Newtonian model seems to overestimate the possibility for the formation of atherosclerotic lesions or aneurysms at sites of the vascular wall where the WSS are oscillating.

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来源期刊
CiteScore
5.90
自引率
0.00%
发文量
1240
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