General well-being in the new decade--important considerations.

Chronic diseases have created a growing burden of ill-health as populations age, become more obese and as survival with many conditions improves. Cardiovascular disease, cancer and anxiety/depression merit priority by being common and treatable. Genomics aid diagnosis and understanding but have limited impact on management. Early diagnosis requires comprehensive annual clinical reviews, in which dental practitioners have an important role. Relevant imaging can be helpful. Useful early interventions include tactical lifestyle measures, weight control, appropriate supplements and low dose pharmacotherapy.