术后疼痛、镇痛药的选择和肠梗阻:一个发展中国家教学医院的快照。

Pub Date : 2022-09-02 eCollection Date: 2022-07-01 DOI:10.1055/s-0042-1755623
Ameer Al-Jasim, Alaa A Aldujaili, Ghaith Al-Abbasi, Hasan Al-Abbasi, Saif Al-Sahee
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引用次数: 1

摘要

缓解疼痛可以通过多种方法来实现,止痛剂是治疗的基本形式。镇痛药的安全性和临床疗效是决定选择镇痛药的核心因素。阿片类药物的一个不良反应是术后肠梗阻(POI)。目的在本研究中,我们观察了巴格达教学医院术后疼痛的严重程度、镇痛药物的类型和POI的发生率。我们假设我们会发现使用的镇痛药类型与POI之间存在关联。方法对巴格达教学医院普通外科住院的100例患者进行观察性研究。采用结构化问卷调查,重点关注镇痛药的类型、疼痛控制程度和肠梗阻的存在。结果69%的患者接受了阿片类药物和非阿片类药物的联合治疗。中度至重度疼痛是疼痛量表上最常见的报告类别。超过一半的患者(57%)在住院期间发现有POI,镇痛类型与POI发展之间存在统计学上显著的关联(p =0.001)。结论阿片类药物和非阿片类药物混合使用是我们中心最常见的方案。在本研究中使用的两种疼痛量表中,大多数外科住院患者报告有中度至重度疼痛。腹部手术后肠梗阻的发生率(61%)明显高于世界范围内报道的发生率(10-30%)。术后肠梗阻有多种原因,其中之一是使用阿片类药物来控制疼痛。考虑到我们中心肠梗阻的高发生率,以及我们发现阿片类药物的使用与肠梗阻之间的关联,进一步的研究应该关注阿片类药物的使用剂量以及替代镇痛方法是否可以减少肠梗阻。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Postoperative Pain, Analgesic Choices, and Ileus: A Snapshot from a Teaching Hospital in a Developing Country.

Background  Pain relief can be achieved by diversity of methods with analgesics being the basic form of treatment. Analgesic safety and clinical effectiveness are the core factors in determining the analgesic of choice. One adverse effect of concern with opioids is the postoperative ileus (POI). Objective  In this study, we looked at the severity of postoperative pain, the type of analgesics used to control the pain, and the incidence of POI at Baghdad Teaching Hospital. We hypothesized that we would find an association between the type of analgesia used and POI. Methods  This observational study was conducted among 100 patients who were residents at the general surgery wards of Baghdad Teaching Hospital. A structured questionnaire was employed focusing on types of analgesics, degree of pain control, and the presence of ileus. Results  Sixty-nine percent of patients received a combination of opioids and nonopioids. Moderate-to-severe pain was the most commonly reported category on pain scales. More than half of the patients (57%) were found to have POI during their hospital stay and there was a statistically significant association between the type of analgesia and POI development ( p =0.001). Conclusions  A mix of analgesics (opioids and nonopioids) was the most common regimen at our center. The majority of the surgical inpatients reported having moderate-to-severe pain on both pain scales used in this study. Ileus incidence following abdominal surgeries (61%) was significantly higher than the reported incidence worldwide (10-30%). Postoperative ileus has multifactorial causes, one of which is the use of opioids for pain control. Considering the high incidence of ileus in our center and the association we found between the use of opioids and ileus, further studies should look at the doses of opioids used and whether alternative analgesic methods might result in less ileus.

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