抗逆转录病毒治疗实现了肝脏艾滋病相关爱泼斯坦-巴尔病毒相关平滑肌肿瘤代谢完全缓解。

IF 1.3 4区医学 Q4 INFECTIOUS DISEASES Antiviral Therapy Pub Date : 2022-10-01 DOI:10.1177/13596535221126828

Takahide Ara, Tomoyuki Endo, Hideki Goto, Kohei Kasahara, Yuta Hasegawa, Shota Yokoyama, Souichi Shiratori, Masao Nakagawa, Ken Kuwahara, Emi Takakuwa, Satoshi Hashino, Takanori Teshima

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引用次数: 3

摘要

eb病毒相关平滑肌肿瘤(EBV-SMT)是一种罕见的间充质肿瘤，多发生于免疫功能低下患者。免疫状态是ebv - smt治疗的重要因素，但抗逆转录病毒治疗(ART)对获得性免疫缺陷综合征(AIDS)相关ebv - smt的疗效尚不清楚。在这里，我们报告了第一例成功的29岁男性肝AIDS相关EBV-SMT仅ART治疗的病例。正电子发射断层扫描对疾病状态的评估是有用的。抗逆转录病毒治疗的最新进展能够迅速恢复患者的免疫状态，这可能会改变艾滋病相关EBV-SMT的治疗策略。

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Antiretroviral therapy achieved metabolic complete remission of hepatic AIDS related Epstein-Barr virus-associated smooth muscle tumor.

Epstein-Barr virus-associated smooth muscle tumor (EBV-SMT) is a rare mesenchymal tumor which occurs in immunocompromised patients. The immune status is an important factor in the treatment of EBV-SMTs, but the efficacy of antiretroviral therapy (ART) is not elucidated in acquired immune deficiency syndrome (AIDS) related EBV-SMTs. Here, we report the first successful case of a 29-year-old man with hepatic AIDS related EBV-SMT treated with ART solely. Positron emission tomography scan was useful for the evaluation of disease status. Recent advances in ART that enables to restore patient's immune status rapidly may change the treatment strategy in AIDS related EBV-SMT.

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来源期刊

Antiviral Therapy 医学-病毒学

CiteScore

2.60

自引率

8.30%

发文量

审稿时长

4-8 weeks

期刊介绍： Antiviral Therapy (an official publication of the International Society of Antiviral Research) is an international, peer-reviewed journal devoted to publishing articles on the clinical development and use of antiviral agents and vaccines, and the treatment of all viral diseases. Antiviral Therapy is one of the leading journals in virology and infectious diseases. The journal is comprehensive, and publishes articles concerning all clinical aspects of antiviral therapy. It features editorials, original research papers, specially commissioned review articles, letters and book reviews. The journal is aimed at physicians and specialists interested in clinical and basic research.