Eva Zhang, Arun Gupta, Aysha Al-Ani, Finlay A Macrae, Rupert W Leong, Britt Christensen
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Logistic regression was used to identify variables associated with vaccine uptake.</p><p><strong>Results: </strong>Of 441 respondents, 93% of respondents had received at least 1 dose of COVID-19 vaccination. Self-perceived risk of being more unwell with COVID-19 infection due to IBD (AOR 5.25, 95% CI 1.96-14.04, <i>p</i> < 0.001) was positively associated with vaccine uptake. Concerns regarding the safety of vaccination in pregnancy (OR 0.22, 95% CI 0.08-0.65, <i>p</i>=0.006) and of causing an IBD flare (OR 0.28, 95% CI 0.10-0.77, <i>p</i>=0.01) were negatively associated with vaccine uptake. In total, 282 (73.7%) responders ranked healthcare workers the most trusted source to obtain information surrounding vaccination.</p><p><strong>Conclusion: </strong>Vaccine hesitancy in IBD patients is low. Concerns about the safety of vaccination in pregnancy and in causing an IBD flare are both associated with vaccine hesitancy. Healthcare providers play a key role in proactively addressing these misconceptions particularly in the context of emerging virus variants and the availability of boosters.</p>","PeriodicalId":48755,"journal":{"name":"Canadian Journal of Gastroenterology and Hepatology","volume":" ","pages":"4527844"},"PeriodicalIF":2.7000,"publicationDate":"2022-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482530/pdf/","citationCount":"2","resultStr":"{\"title\":\"Misconceptions Drive COVID-19 Vaccine Hesistancy in Individuals with Inflammatory Bowel Disease.\",\"authors\":\"Eva Zhang, Arun Gupta, Aysha Al-Ani, Finlay A Macrae, Rupert W Leong, Britt Christensen\",\"doi\":\"10.1155/2022/4527844\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Vaccination is an effective public health measure to combat the SARS-CoV-2 pandemic. However, vaccine \\\"hesitancy\\\" has limited uptake in some, including inflammatory bowel disease (IBD) patients who may have unique concerns influencing uptake.</p><p><strong>Aim: </strong>The aim of the study is to explore attitudes, concerns, and the influence of different sources of information on COVID-19 vaccine uptake in IBD patients.</p><p><strong>Methods: </strong>Patients from a specialist IBD clinic at a tertiary hospital in Australia and a national IBD patient society were invited to complete an anonymous online survey regarding COVID-19 vaccination. Demographic characteristics, attitudes towards vaccination, and trust in sources of information were explored. Logistic regression was used to identify variables associated with vaccine uptake.</p><p><strong>Results: </strong>Of 441 respondents, 93% of respondents had received at least 1 dose of COVID-19 vaccination. Self-perceived risk of being more unwell with COVID-19 infection due to IBD (AOR 5.25, 95% CI 1.96-14.04, <i>p</i> < 0.001) was positively associated with vaccine uptake. Concerns regarding the safety of vaccination in pregnancy (OR 0.22, 95% CI 0.08-0.65, <i>p</i>=0.006) and of causing an IBD flare (OR 0.28, 95% CI 0.10-0.77, <i>p</i>=0.01) were negatively associated with vaccine uptake. In total, 282 (73.7%) responders ranked healthcare workers the most trusted source to obtain information surrounding vaccination.</p><p><strong>Conclusion: </strong>Vaccine hesitancy in IBD patients is low. Concerns about the safety of vaccination in pregnancy and in causing an IBD flare are both associated with vaccine hesitancy. Healthcare providers play a key role in proactively addressing these misconceptions particularly in the context of emerging virus variants and the availability of boosters.</p>\",\"PeriodicalId\":48755,\"journal\":{\"name\":\"Canadian Journal of Gastroenterology and Hepatology\",\"volume\":\" \",\"pages\":\"4527844\"},\"PeriodicalIF\":2.7000,\"publicationDate\":\"2022-09-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482530/pdf/\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Canadian Journal of Gastroenterology and Hepatology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1155/2022/4527844\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2022/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Canadian Journal of Gastroenterology and Hepatology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1155/2022/4527844","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 2
摘要
背景:疫苗接种是抗击SARS-CoV-2大流行的有效公共卫生措施。然而,疫苗“犹豫”限制了一些人的吸收,包括炎症性肠病(IBD)患者,他们可能有影响吸收的独特因素。目的:本研究旨在探讨不同信息来源对IBD患者COVID-19疫苗接种的态度、关注和影响。方法:邀请来自澳大利亚某三级医院IBD专科诊所和国家IBD患者协会的患者完成关于COVID-19疫苗接种的匿名在线调查。探讨了人口统计学特征、对疫苗接种的态度以及对信息来源的信任。Logistic回归用于确定与疫苗摄取相关的变量。结果:在441名受访者中,93%的受访者至少接种了1剂COVID-19疫苗。因IBD感染COVID-19而感到更不适的自我感知风险(AOR 5.25, 95% CI 1.96-14.04, p < 0.001)与疫苗接种呈正相关。对妊娠期疫苗接种安全性的担忧(OR 0.22, 95% CI 0.08-0.65, p=0.006)和引起IBD爆发的担忧(OR 0.28, 95% CI 0.10-0.77, p=0.01)与疫苗接种呈负相关。总共有282名应答者(73.7%)将卫生保健工作者列为获得疫苗接种相关信息的最可信来源。结论:IBD患者的疫苗犹豫率较低。对妊娠期疫苗接种安全性和引起IBD爆发的担忧都与疫苗犹豫有关。医疗保健提供者在主动解决这些误解方面发挥着关键作用,特别是在新出现的病毒变体和增强剂可用性的背景下。
Misconceptions Drive COVID-19 Vaccine Hesistancy in Individuals with Inflammatory Bowel Disease.
Background: Vaccination is an effective public health measure to combat the SARS-CoV-2 pandemic. However, vaccine "hesitancy" has limited uptake in some, including inflammatory bowel disease (IBD) patients who may have unique concerns influencing uptake.
Aim: The aim of the study is to explore attitudes, concerns, and the influence of different sources of information on COVID-19 vaccine uptake in IBD patients.
Methods: Patients from a specialist IBD clinic at a tertiary hospital in Australia and a national IBD patient society were invited to complete an anonymous online survey regarding COVID-19 vaccination. Demographic characteristics, attitudes towards vaccination, and trust in sources of information were explored. Logistic regression was used to identify variables associated with vaccine uptake.
Results: Of 441 respondents, 93% of respondents had received at least 1 dose of COVID-19 vaccination. Self-perceived risk of being more unwell with COVID-19 infection due to IBD (AOR 5.25, 95% CI 1.96-14.04, p < 0.001) was positively associated with vaccine uptake. Concerns regarding the safety of vaccination in pregnancy (OR 0.22, 95% CI 0.08-0.65, p=0.006) and of causing an IBD flare (OR 0.28, 95% CI 0.10-0.77, p=0.01) were negatively associated with vaccine uptake. In total, 282 (73.7%) responders ranked healthcare workers the most trusted source to obtain information surrounding vaccination.
Conclusion: Vaccine hesitancy in IBD patients is low. Concerns about the safety of vaccination in pregnancy and in causing an IBD flare are both associated with vaccine hesitancy. Healthcare providers play a key role in proactively addressing these misconceptions particularly in the context of emerging virus variants and the availability of boosters.
期刊介绍:
Canadian Journal of Gastroenterology and Hepatology is a peer-reviewed, open access journal that publishes original research articles, review articles, and clinical studies in all areas of gastroenterology and liver disease - medicine and surgery.
The Canadian Journal of Gastroenterology and Hepatology is sponsored by the Canadian Association of Gastroenterology and the Canadian Association for the Study of the Liver.