咖啡和血压:令人兴奋的消息!

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2022-12-01 DOI:10.1080/08037051.2022.2136621
Claudio Borghi
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引用次数: 7

摘要

越来越多的流行病学研究报告了习惯性饮用咖啡对心血管疾病(CVD)和死亡率的有益影响。然而,咖啡对动脉高血压的影响仍然是积极讨论的对象,主要是因为咖啡因对血压和心血管系统的影响存在争议。特别是,咖啡因的负面影响会涉及到整个心血管系统,并可能导致新发高血压的相对风险过高,以及血压控制的恶化。最近发表的证据排除了咖啡对高血压发展和高血压控制的显著影响,支持咖啡的抗氧化成分的保护作用,可能抵消咖啡因所声称的负面作用。咖啡中咖啡因和保护心脏的化学成分的存在和数量在很大程度上取决于咖啡的种类、生产和制备方法,这可以部分解释关于咖啡摄入对血压和心血管系统影响的不同观点。此外,咖啡因代谢的某些遗传方面可能导致已发表证据的异质性,而最新的心血管指南在很大程度上支持高血压和心血管疾病的咖啡饮用。这篇简短综述的目的是简要总结一些最近在咖啡和血压方面的文献信息。根据大量的观察证据,我们可以提出:•虽然非习惯性饮用咖啡的急性饮用可能会导致血压升高,但习惯性饮用中高剂量的咖啡(每天3到5杯)对血压值和新发高血压的影响是中性的,甚至是有益的。•同样的摄入量可显著降低心血管疾病的发病率和全因死亡率。•饮用咖啡符合正确和平衡的生活方式,因此不应阻止高血压和心血管疾病患者。
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Coffee and blood pressure: exciting news!

A growing number of epidemiological studies have reported the beneficial effects of habitual coffee consumption on incident cardiovascular disease (CVD), and mortality. However, the effects of coffee on arterial hypertension are still objects of active discussion mainly because of the debated effects of caffeine on blood pressure and cardiovascular system. In particular, the negative impact of caffeine would involve the whole cardiovascular system and could be responsible for an excess in the relative risk of new onset of hypertension and a worsening of blood pressure control. Recent evidence has been published excluding a significant effect of coffee consumption on hypertension development and blood pressure control in treated and untreated hypertensive supporting a protective role for the antioxidant components of coffee that may counteract the claimed negative effect of caffeine. The presence and amount of caffeine and cardio-protective chemical constituents of coffee is largely dependent on the type, production, and method of preparation and this can partially explain the divergent opinions on the effects of coffee intake on blood pressure and cardiovascular system. In addition, some genetic aspect of caffeine metabolism can contribute to the heterogeneity of published evidence while the most recent cardiovascular guidelines largely endorse coffee consumption in hypertension and CV disease. The purpose of this short review is to briefly summarise some of the recent information available in the literature on coffee and blood pressure.Key points  According to the considerable amount of observational evidence we can suggest that:  • While acute coffee administration in non-habitual users may induce a blood pressure rise, habitual coffee consumption in medium-high dosages (from 3 to 5 cups/day), has neutral or even beneficial impact on blood pressure values and the new onset of hypertension.   • The same intake significantly reduces the incidence of cardiovascular disease, as well as all-cause mortality.   • The consumption of coffee is compatible with a correct and balanced lifestyle and should therefore not be discouraged in subjects with hypertension and cardiovascular diseases.

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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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