尼日利亚西南部城市社区Ogbomosho 2型糖尿病患者贫血的患病率和模式

IF 2.2 Q3 HEMATOLOGY Anemia Pub Date : 2022-10-26 eCollection Date: 2022-01-01 DOI:10.1155/2022/7650015
Kehinde J Olufemi-Aworinde, Tolulase A Olutogun, Joel O Akande, Roseline O Akande, Abiona O Odeyemi, Olufemi J Idowu, Elizabeth O Oke, Ademola T Abolarin, Oluwabukola A Ala
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引用次数: 0

摘要

贫血是2型糖尿病的常见病,但通常与慢性肾脏疾病和肾功能不全一起出现。贫血先于肾功能不全的病例与2型糖尿病患者预后较差和并发症易感性增加有关。本研究旨在确定在我们的环境中没有慢性肾脏疾病的2型糖尿病患者贫血的患病率和类型。该研究是一项以医院为基础的横断面研究,141名已知的2型糖尿病患者作为研究组,140名健康人作为对照组。研究人群和对照组采用多阶段抽样技术进行选择。数据在Ogbomosho博文大学教学医院内分泌科门诊采用访谈者管理的半结构化问卷收集。采用IBM SPSS 23.0版本对所得数据进行分析(p值≤0.05为显著)。生化指标(空腹血脂、HBA1C、FBG、血清白蛋白、肌酐、尿素、尿酸、胰岛素)和血液学指标(FBC、红细胞指标);采用标准方法对调查对象的PVC、MCV、MCH、MCHC和RCDW参数进行分析。研究显示,研究对象之间的贫血患病率有统计学上的显著差异,为69.2%,而对照组为30.8%。正常红细胞贫血在受试者中占主导地位,而小细胞低色素贫血在对照组中占主导地位。两组间MCV、MCHC差异无统计学意义。研究对象的贫血发生率与糖尿病病程呈正相关。现在越来越多的2型糖尿病患者寿命更长,血液学参数的增加应该成为他们基线调查的一部分,以帮助早期发现并发症。
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The Prevalence and Pattern of Anaemia in Type 2 Diabetics in Ogbomosho, An Urban Community in Southwestern Nigeria.

Anaemia is a frequent finding in type 2 diabetes, but it is typically seen with established chronic kidney disease and renal insufficiency. Cases, where anaemia predates renal insufficiency, are associated with a worse prognosis for the type 2 diabetes patient and an increased susceptibility to complications. This study aims to determine the prevalence and type of anaemia in persons living with type 2 diabetes without established chronic kidney disease in our environment. The study was a hospital-based cross-sectional study that involved 141 people with known type 2 diabetes as the study group and 140 healthy persons as controls. The study population and the controls were selected using a multistage sampling technique. Data were collected using an interviewer-administered semistructured questionnaire at the Endocrinology clinic, Bowen University Teaching Hospital, Ogbomosho. The data obtained were analyzed using the IBM SPSS version 23.0 (p value ≤0.05 was considered significant). The biochemical (fasting lipids, HBA1C, FBG, serum albumin, creatinine, urea, uric acid, and insulin) and haematological (FBC and red cell indices; PVC, MCV, MCH, MCHC, and RCDW) parameters of the respondents were analyzed using standard methods. The study showed a statistically significant difference in the prevalence of anaemia among subjects, 69.2% as compared to 30.8% of the control group. Normochromic normocytic anaemia was predominant among the subjects, whereas microcytic hypochromic anaemia was the predominant type in the controls. There was no statistically significant difference between MCV and MCHC of both subjects and controls. There was a positive correlation between the incidence of anaemia and the duration of diabetes among the subjects. More people with type 2 diabetes are now living longer, and the addition of haematological parameters should be part of their baseline investigations to aid in the early detection of complications.

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来源期刊
Anemia
Anemia HEMATOLOGY-
CiteScore
4.80
自引率
3.40%
发文量
11
审稿时长
18 weeks
期刊介绍: Anemia is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies on all types of anemia. Articles focusing on patient care, health systems, epidemiology, and animal models will be considered, among other relevant topics. Affecting roughly one third of the world’s population, anemia is a major public health concern. The journal aims to facilitate the exchange of research addressing global health and mortality relating to anemia and associated diseases.
期刊最新文献
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