门诊耳鼻咽喉头颈外科手术后普遍存在阿片类镇痛药物处方过量的现象:一项多中心研究。

Q2 Medicine World Journal of OtorhinolaryngologyHead and Neck Surgery Pub Date : 2022-03-09 eCollection Date: 2022-06-01 DOI:10.1002/wjo2.19
Amr F Hamour, Frederick Laliberte, Jordan Levy, Jason Xu, Edward Park, Vincent Lin, John de Almeida, Julie Strychowsky, Antoine Eskander, Eric Monteiro
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引用次数: 0

摘要

背景:在加拿大和美国,使用处方阿片类药物进行术后镇痛的手术越来越多,这反映了阿片类药物相关发病率的上升趋势。本研究对接受耳鼻咽喉头颈外科手术的择期手术患者的每日疼痛程度和术后用药需求进行了前瞻性研究:方法:要求患者前瞻性地记录术后 7 天内每天的疼痛程度和用药情况。最后的调查用于量化留在家中的未用药物,并明确每位患者的处理计划。我们纳入了2016年9月至2017年9月在安大略省多伦多市三家三级医疗中心接受择期门诊手术或短期住院手术的患者。曾使用过阿片类药物或患有慢性疼痛的患者被排除在外:研究最终纳入了56名符合条件的成年患者。最常见的手术是甲状腺切除术(19 例)、内窥镜鼻窦手术(10 例)、鼓室成形术/鼻腔成形术(7 例)和人工耳蜗植入术(5 例)。大多数患者的处方为对乙酰氨基酚/可待因(29 人,占 51.8%)或对乙酰氨基酚/羟考酮(22 人,占 39.3%),平均使用了其初始处方的 29%。患者最常选择将未使用的麻醉剂放在家中(23 人,41%)。在我们的研究人群中,共超量开出了 710 片麻醉药,其中 351 片被保存在患者家中,以供日后使用:结论:耳鼻喉科医生明显倾向于高估术后疼痛,导致阿片类药物处方严重超量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Overprescription of opioid analgesia is common following ambulatory Otolaryngology-Head and Neck surgery procedures: A multicenter study.

Background: The rise in the use of prescription opioids for postoperative analgesia within surgery has mirrored an increased trend of opioid-related morbidity within Canada and the United States. This study prospectively studied daily pain levels and medication requirements postoperatively in patients undergoing elective Otolaryngology-Head and Neck surgery procedures.

Methods: Patients were asked to prospectively document their pain level and medication use daily for 7 days postoperatively. A final survey was used to quantify unused medication left at home and clarify each patient's disposal plan. We included patients undergoing elective outpatient or short stay surgeries from three tertiary care centers in Toronto, Ontario from September 2016 to September 2017. Previous opioids users or patients suffering from chronic pain were excluded.

Results: A final cohort of 56 eligible adult patients were included in the study. The most common procedures were thyroidectomy (n = 19), endoscopic sinus surgery (n = 10), tympanoplasty/ossiculoplasty (n = 7), and cochlear implant (n = 5). Most patients received a prescription for acetaminophen/codeine (n = 29, 51.8%) or acetaminophen/oxycodone (n = 22, 39.3%) and used on average 29% of their initial prescription. Patients most commonly opted to keep their unused narcotics at home (n = 23, 41%). A total of 710 tablets of narcotics were overprescribed in our study population, 351 of which were kept in patients' home for future use.

Conclusion: There is a clear tendency to overestimate postoperative pain resulting in significant overprescription of opioids among Otolaryngologists.

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审稿时长
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