补充秋葵提取物对糖尿病肾病患者膳食摄入量、食欲、人体测量和体成分的影响

IF 2.4 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Health Promotion Perspectives Pub Date : 2022-08-20 eCollection Date: 2022-01-01 DOI:10.34172/hpp.2022.21
Omid Nikpayam, Ehsan Safaei, Nazgol Bahreyni, Vahideh Sadra, Maryam Saghafi-Asl, Laleh Fakhr
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引用次数: 1

摘要

背景:糖尿病是慢性肾脏疾病的危险因素,因为它会诱发肾病。秋葵是抗氧化剂、维生素、矿物质和纤维的丰富来源,在许多动物研究中都有对糖尿病有益的报道。本试验旨在探讨补充干秋葵提取物(DOE)对糖尿病肾病(DN)患者的人体测量、身体组成、食欲和饮食摄入的影响。方法:在这项三盲安慰剂对照随机临床试验中,64例DN患者随机分配接受125 mg DOE胶囊(n=32)或安慰剂(n=32),为期10周。在试验的基线和终点,对人体测量变量、身体成分指数、饮食摄入和食欲评分进行评估。结果:结果显示,与基线值相比,DOE组在终点时能量(P=0.047, CI: -425.87, -3.25, ES: 0.539)和碳水化合物(P=0.038, CI: -85.64, -2.53, ES: 0.555)摄入和吃咸食物的欲望(P=0.023)减少。然而,人体测量、身体成分和食欲评分在两个研究组之间没有显著差异。结论:本临床试验表明,DOE可显著降低DN患者的能量摄入和碳水化合物消耗。需要进一步的临床试验来确定这种补充剂的效果。
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The effect of Abelmoschus esculentus L. (Okra) extract supplementation on dietary intake, appetite, anthropometric measures, and body composition in patients with diabetic nephropathy.

Background: Diabetes is a risk factor for chronic kidney disease because it induces nephropathy. Okra is a rich source of antioxidants, vitamins, minerals, and fibers, of which favorable effects in diabetes have been reported in many animal studies. The present trial aimed to investigate the effect of dried okra extract (DOE) supplementation on anthropometric measures, body composition, appetite, and dietary intake in diabetic nephropathy (DN) patients. Methods: In this triple-blind placebo-controlled randomized clinical trial, 64 DN patients were randomly allocated to receive a 125-mg capsule of DOE (n=32) or placebo (n=32) for 10 weeks. At baseline and endpoint of the trial, anthropometric variables, body composition indices, dietary intake, and appetite scores were evaluated. Results: The results showed that energy (P=0.047, CI: -425.87, -3.25, ES: 0.539) and carbohydrate (P=0.038, CI: -85.64, -2.53, ES: 0.555) intake as well as desire to eat salty food (P=0.023) were reduced in DOE group at the endpoint, compared to the baseline values. However, anthropometric measures, body composition, and appetite score were not significantly different between the two study groups. Conclusion: In conclusion, the present clinical trial showed that DOE could significantly decrease energy intake and carbohydrate consumption in the DN patients. Further clinical trials are needed to determine the effects of this supplement.

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来源期刊
Health Promotion Perspectives
Health Promotion Perspectives PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
7.10
自引率
2.30%
发文量
27
审稿时长
13 weeks
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