冠状动脉ct在动脉粥样硬化钙筛查中的应用。

IF 1.9 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Heart International Pub Date : 2020-12-17 eCollection Date: 2020-01-01 DOI:10.17925/HI.2020.14.2.76
Joshua Beverly, Matthew J Budoff
{"title":"冠状动脉ct在动脉粥样硬化钙筛查中的应用。","authors":"Joshua Beverly,&nbsp;Matthew J Budoff","doi":"10.17925/HI.2020.14.2.76","DOIUrl":null,"url":null,"abstract":"<p><p>Coronary artery calcium (CAC) scoring serves as a highly specific marker of coronary atherosclerosis. Based on the results of multiple large-scale, longitudinal population-based studies, CAC scoring has emerged as a reliable predictor of atherosclerotic cardiovascular disease (ASCVD) presence and risk assessment in asymptomatic patients across all age, sex and racial groups. Therefore, the measurement of CAC is useful in guiding clinical decision-making for primary prevention (e.g. use of statin and aspirin). This tool has already been incorporated into the clinical guidelines and is steadily being integrated into standard clinical practice. The adoption of CAC scoring will be important for curbing the progressive burden that ASCVD is exerting on our healthcare system. It has already been projected that CAC testing will decrease healthcare spending and will hopefully be shown to improve ASCVD outcomes. The purpose of this review is to summarise the evidence regarding calcium screening for atherosclerosis, particularly in asymptomatic individuals, including the pathophysiology, the prognostic power of CAC in the context of population-based studies, the progressive inclusion of CAC into clinical guidelines and the existing concerns of cost and radiation.</p>","PeriodicalId":12836,"journal":{"name":"Heart International","volume":"14 2","pages":"76-79"},"PeriodicalIF":1.9000,"publicationDate":"2020-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562964/pdf/heart-int-14-76.pdf","citationCount":"0","resultStr":"{\"title\":\"Use of Coronary Computed Tomography for Calcium Screening of Atherosclerosis.\",\"authors\":\"Joshua Beverly,&nbsp;Matthew J Budoff\",\"doi\":\"10.17925/HI.2020.14.2.76\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Coronary artery calcium (CAC) scoring serves as a highly specific marker of coronary atherosclerosis. Based on the results of multiple large-scale, longitudinal population-based studies, CAC scoring has emerged as a reliable predictor of atherosclerotic cardiovascular disease (ASCVD) presence and risk assessment in asymptomatic patients across all age, sex and racial groups. Therefore, the measurement of CAC is useful in guiding clinical decision-making for primary prevention (e.g. use of statin and aspirin). This tool has already been incorporated into the clinical guidelines and is steadily being integrated into standard clinical practice. The adoption of CAC scoring will be important for curbing the progressive burden that ASCVD is exerting on our healthcare system. It has already been projected that CAC testing will decrease healthcare spending and will hopefully be shown to improve ASCVD outcomes. The purpose of this review is to summarise the evidence regarding calcium screening for atherosclerosis, particularly in asymptomatic individuals, including the pathophysiology, the prognostic power of CAC in the context of population-based studies, the progressive inclusion of CAC into clinical guidelines and the existing concerns of cost and radiation.</p>\",\"PeriodicalId\":12836,\"journal\":{\"name\":\"Heart International\",\"volume\":\"14 2\",\"pages\":\"76-79\"},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2020-12-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562964/pdf/heart-int-14-76.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Heart International\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.17925/HI.2020.14.2.76\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2020/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Heart International","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17925/HI.2020.14.2.76","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2020/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0

摘要

冠状动脉钙(CAC)评分是冠状动脉粥样硬化的高度特异性标志物。基于多个大规模、纵向人群研究的结果,CAC评分已成为所有年龄、性别和种族的无症状患者动脉粥样硬化性心血管疾病(ASCVD)存在和风险评估的可靠预测指标。因此,测量CAC对指导一级预防的临床决策(例如使用他汀类药物和阿司匹林)是有用的。该工具已被纳入临床指南,并正在稳步整合到标准临床实践中。采用CAC评分对于抑制ASCVD对我们医疗系统的累进负担非常重要。已经有人预测,CAC检测将减少医疗保健支出,并有望改善ASCVD结果。本综述的目的是总结关于动脉粥样硬化钙筛查的证据,特别是在无症状个体中,包括病理生理学、基于人群的研究背景下CAC的预后能力、CAC逐渐纳入临床指南以及现有的成本和辐射问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Use of Coronary Computed Tomography for Calcium Screening of Atherosclerosis.

Coronary artery calcium (CAC) scoring serves as a highly specific marker of coronary atherosclerosis. Based on the results of multiple large-scale, longitudinal population-based studies, CAC scoring has emerged as a reliable predictor of atherosclerotic cardiovascular disease (ASCVD) presence and risk assessment in asymptomatic patients across all age, sex and racial groups. Therefore, the measurement of CAC is useful in guiding clinical decision-making for primary prevention (e.g. use of statin and aspirin). This tool has already been incorporated into the clinical guidelines and is steadily being integrated into standard clinical practice. The adoption of CAC scoring will be important for curbing the progressive burden that ASCVD is exerting on our healthcare system. It has already been projected that CAC testing will decrease healthcare spending and will hopefully be shown to improve ASCVD outcomes. The purpose of this review is to summarise the evidence regarding calcium screening for atherosclerosis, particularly in asymptomatic individuals, including the pathophysiology, the prognostic power of CAC in the context of population-based studies, the progressive inclusion of CAC into clinical guidelines and the existing concerns of cost and radiation.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Heart International
Heart International Medicine-Cardiology and Cardiovascular Medicine
CiteScore
0.90
自引率
0.00%
发文量
9
审稿时长
7 weeks
期刊最新文献
Efficacy of Commonly Used 3D Mapping Systems in Acute Success Rates of Catheter Ablation Procedures. Evolution of Disease-modifying Therapy for Transthyretin Cardiac Amyloidosis. Femoral Neck Osteoporosis Is Associated with a Higher Odds of Coronary Artery Disease in Indian Postmenopausal Women: A Cross-sectional Study from a Teaching Hospital in Southern India. Cardiovascular Implications of Semaglutide in Obesity Management: Redefining Cardiovascular Health Strategies. A Comprehensive Evaluation of the NAVITOR Transcatheter Aortic Valve Replacement System.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1