州精神病院法医住院病人的抗精神病药物因素与时间到能力的关系。

The Mental Health Clinician Pub Date : 2022-06-10 eCollection Date: 2022-06-01 DOI:10.9740/mhc.2022.06.175
Amber Lemons, Courtney A Iuppa, Carrie R Kriz, Lauren A Diefenderfer, Leigh Anne Nelson, Shelby E Lang, Ellie S R Elliott, Joseph Moon, Roger W Sommi
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摘要

对被认定无能力受审的被告人,可以进行包括心理健康治疗和法律教育在内的能力恢复。抗精神病药物常用于治疗;然而,很少有数据能证明它们的作用。方法:本回顾性研究纳入了2016年7月至2020年2月期间被认为有能力接受审判并服用抗精神病药物的受试者。主要转归是抗精神病药物在时间到能力上的差异。次要结果包括抗精神病药物组之间从时间到能力的差异,根据监狱药物可用性、个体抗精神病药物和处方判断能力后停留时间的差异。结果:纳入117例受试者进行分析。在个体抗精神病药物、第一代和第二代抗精神病药物或制剂之间,从时间到能力没有差异。对于服用长效注射抗精神病药物的受试者(103天对56天),在监狱中无法接受抗精神病药物的受试者(104天对54天),或服用任何处方帕利哌酮而不是奥氮平的受试者(88天对35天),在判断能力后的停留时间明显更长。讨论:由于时间对胜任力的影响不存在差异,因此在选择胜任力恢复代理时应考虑患者的具体因素。逗留时间的差异可能与监狱和州立精神病院之间抗精神病药物使用的差异有关。因此,与获得抗精神病药物相关的政策应该更好地协调国家精神病院和监狱,以提高系统的能力并提供更好的护理。
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Antipsychotic factors related to time to competency for forensic inpatients in a state psychiatric facility.

Introduction: A defendant who is deemed incompetent to stand trial may go through competency restoration consisting of mental health treatment and legal education. Antipsychotics are often used in treatment; however, there is little data examining their role.

Methods: This retrospective study included subjects opined competent to stand trial from July 2016 to February 2020 and prescribed an antipsychotic. The primary outcome was difference in time to competency between antipsychotics. Secondary outcomes included difference in time to competency between groups of antipsychotics, difference in length of stay after opined competent based on medication availability in jail, individual antipsychotics, and formulations.

Results: There were 117 subjects included for analysis. There were no differences in time to competency between individual antipsychotics, first- and second-generation antipsychotics, or formulations. Length of stay after opined competent was significantly longer for subjects who were prescribed a long-acting injectable antipsychotic (103 days vs 56 days), who were not able to receive their antipsychotic in jail (104 days vs 54 days), or who were prescribed any formulation of paliperidone compared with olanzapine (88 days vs 35 days).

Discussion: Since there were no differences in time to competency, patient-specific factors should be used to choose an agent for competency restoration. Length of stay differences are likely related to the antipsychotic access differences between jails and state psychiatric facilities. Therefore, policies related to antipsychotic access should better align between state psychiatric facilities and jails to improve the capacity of the system and provide better care.

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