骨髓移植后免疫功能低下儿童患者的弓形虫病绒毛膜视网膜炎模拟巨细胞病毒视网膜炎。

GMS ophthalmology cases Pub Date : 2022-06-07 eCollection Date: 2022-01-01 DOI:10.3205/oc000201
Anubhav Garg, Bryon R McKay, Carolina L M Francisconi, Rajeev H Muni
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引用次数: 1

摘要

目的:回顾1例骨髓移植后免疫功能低下患者发生类似巨细胞病毒视网膜炎的弓形虫病绒毛膜视网膜炎。方法:回顾性分析一名14岁女性,在出现眼部症状前曾有白血病和异基因骨髓移植史。结果:前房液检测弓形虫阳性。当巨细胞病毒性视网膜炎治疗转为玻璃体注射克林霉素与全身磺胺嘧啶和强的松时,患者反应良好。结论:本病例显示了在免疫功能低下患者中诊断和治疗视网膜感染的挑战,因为他们可能表现出模仿其他病理的非典型表现,并且可能有标准治疗的禁忌症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Toxoplasmosis chorioretinitis mimicking cytomegalovirus retinitis in an immunocompromised pediatric patient following bone marrow transplantation.

Objective: To review a case of toxoplasmosis chorioretinitis mimicking cytomegalovirus retinitis in an immunocompromised patient following bone marrow transplantation.

Methods: Retrospective chart review of a 14-year-old female who had a history of leukemia and allogeneic bone marrow transplants prior to her ocular symptoms.

Results: Anterior chamber fluid analysis was positive for Toxoplasma gondii. The patient responded well when cytomegalovirus retinitis treatment was switched to intravitreal clindamycin with systemic sulfadiazine and prednisone.

Conclusions: This case demonstrates the challenges of diagnosing and treating retinal infections in immunocompromised patients as they may present with atypical findings that mimic other pathologies and may have contraindications against standard treatment.

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